Yeah, I'd definitely start Eriksen tomorrow with Fernandes unavailable.
Charlton will be defending deep, and will be a packed, reasonably organised defence. It will require moments of skill and vision from some of our more technically gifted players to break them down. The likes of Fred, McTominay, Iqbal, Elanga, etc, aren't going to produce those moments as the main ball players.
They'll play their role with the ball, but I'd like to see some of the likes of Eriksen, Antony, Rashford, Martial, etc, starting as well - in order to provide the quality on the ball that should make the difference.
Rashford should probably only be used as a sub - if needed at all. But Antony and Martial could do with the boost of a decent performance / producing end product, and Eriksen is needed for his quality on the ball with Fernandes missing, and the likes of Casimero and Rashford probably rested.