Still do not see the logic of reopening the pubs on a Saturday. Surely a Monday would be a better phased return. Seems to me like the outcome is going to be obvious. Mass gatherings, massive increase in accident and emergency admittance followed by big headlines blaming the UK population for any second peak. When the reality is the government have fecked this at every junction.
SARS CoV-2 coronavirus / Covid-19 (No tin foil hat silliness please)
- Thread starter Don't Kill Bill
- Start date
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In the latest episode of the United Hour Podcast, Nik and Imran hold a long overdue conversation about United's awful league form with 1 win in 7. They discuss a disappointing draw at Bournemouth, a not so disappointing draw against Liverpool and a crushing defeat at Chelsea - Is time nearly over for Erik Ten Hag?
Then in a special second half of the pod, Nik welcomes Natalie ( https://twitter.com/natalie_17) to discuss the fortunes of Manchester United Women as they booked a place in the FA Cup Final after a historic first ever win vs. Chelsea.
Haven’t read this thread in months. I just wanted to forget the ache and dullness.. I cannot describe the feeling but I felt like the more I talked about the more I felt sick.
Anyway, I’m just saying, my friend and I have started prepping for second wave. I know I sound like a loony but we’ve seen it before and we’re genuinely doomsday preparing. It’s absolutely fecking mental but you have to ask yourself how many mental things have you experienced in the last 12 months? Is something as crazy as this is truly out of the realms of possibility?
Anyway, I’m just saying, my friend and I have started prepping for second wave. I know I sound like a loony but we’ve seen it before and we’re genuinely doomsday preparing. It’s absolutely fecking mental but you have to ask yourself how many mental things have you experienced in the last 12 months? Is something as crazy as this is truly out of the realms of possibility?
"Let's not blow it"
says Boris Johnson on the eve of lockdown easing.
- says General Custer wearing a tomahawk as a trilby.
- says Hitler to the barrel pressed against his temple.
- says Edward Smith from within Davey Jones' locker.
My guys, you done blown it, like it was made of fecking straw.
says Boris Johnson on the eve of lockdown easing.
- says General Custer wearing a tomahawk as a trilby.
- says Hitler to the barrel pressed against his temple.
- says Edward Smith from within Davey Jones' locker.
My guys, you done blown it, like it was made of fecking straw.
Boris did a great job according to himself.
Trump the same.
The Brazilian president as well.
When world leaders don't care this is what happens.
It's going to be 10 years before the world starts to recover from the damage this poxy virus is going to do. We're only at the start.
What does that involve?
Melbourne struggling to contain an outbreak. 100 new cases today and 2 more postcodes added to the 10 already returned to stage 3 lockdown. Plus 9 public housing blocks gone to full lockdown - residents can't leave for any reason. Rotating shifts of 500 police at a time enforcing the towerblock lockdown.
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When your head is already far too big for your face, it’s a strange decision to inflate the rest of your body to exaggerate the deformity.
Modi in India as well.
That photo has been doing the rounds for at least a year
https://thetab.com/uk/2020/06/10/we...re-and-theyve-had-enough-of-your-jokes-161026
Do they get food delivered to them?
I feel bad now
And so you should.I feel bad now
We've all done it.
But most of us remember to switch the camera off.Tweet
— Twitter API (@user) date
I love the thought of the frantic colleagues calling him.
Tweet
— Twitter API (@user) date
Yay for the UK. No masks, chatting away like nothing's happening. Idiots.
I'd assume so.
Although if there are any refugees in there Peter Dutton (our Minister for victimising ethnic minorities) would probably prefer to starve them and deport them to a gulag in a developing nation.
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We've all left clothes in the tumble dryer too long.
Just reading about that. Not allowed to leave for any reason. Food and essential supplies delivered to them. Feck me that’s hardcore. Wuhan style. Were they that strict when the whole country was in lockdown?
In Italy you can take the mask off when you're at your table (can't eat or drink with a mask on), but you put it on again if you get up to go anywhere else in the restaurant or bar. Staff are wearing masks all the time.
Thought they said clients and hairdressers should wear masks. I know a hairdresser and her staff are all going to wear masks, only two stylist in at a time.
No. We had level 3 restrictions where you could only leave home to shop for food etc
And there is a great deal of support for further lockdowns, except from the Federal Government who are far right wing feckwits, so it is to be expected that they are finding it hard to priorities the scientific and medical consensus. We were actually lucky that they had been so incompetent prior to covid as they wouldn't have thrown their ideology to the wind as easily if there weren't in last chance saloon.
I've been to the hairdressers since it was allowed here in Italy - we both wore masks (she wore a face shield, actually) and gloves. There was hand sanitiser available at the door and disposable gloves. The salon was cleaner than most British hospitals.
It is perfectly possible to have a hair cut and wear a mask at the same time.
It is pretty obvious you are not going to get it zero for a period of over a month. No reason for further lockdowns. Just keep it at low manageable level like Nordics and Germany for example.
I don't fecking know, I think they're just trying to score some political points because people love going to Croatia for their vacations and many don't seem to be taking COVID-19 seriously anymore.
Anyway, we're predictably back to 30 cases a day as of yesterday. A complete lack of sensible post-lockdown leadership has finally caught up with us. The border with Croatia has still not been closed despite the fact that the majority of our cases have been brought in from Croatia. Many are still going on their vacations to Croatian coastline as of this weekend. It's ridiculous. There has been talk of closing the indoor public spaces again on Monday. We've managed to get a second wave going purely because out leadership didn't want to be the bad guys and explain to the public that they should change their vacation plans, the fecking morons.
That's the government's plan all along.
Win their brownie points for the public to vote for them in the next election.
Any government with a few brain cells would think it would be smartest to open on a Monday to see how it all plays out in a quieter sense, but Boris only cares about giving the idiots what the want, without any virus thoughts kicking in...
Rubbish. Most states are at zero. Even NSW are close. Victoria, where there have been 50-100 new infection this week, the vast majority of cases are attached to known clusters or in quarantine after arriving from overseas.
And Germany and Nordic have a far higher infection rate.
Yes it is possible, that's why you see people wearing masks and visors here in the UK too.
Does anyone here know what the shortest time phase 1/phase 2 trial of a vaccine can be completed in?
India's national medical institute has bizarrely said they want a public rollout of a vaccine in 45 days from now, with phase 1 trials starting on July 7th. I can see that's not possible, but what is actually the shortest period of time for a vaccine to go from phase 1 to approval?
Phase 3 as I understand it is about testing efficacy, which is a function of N and infection rate. If you choose a sufficiently large N and happen to choose a city of high infections, I can imagine phase 3 could be completed pretty rapidly. Am I wrong?
India's national medical institute has bizarrely said they want a public rollout of a vaccine in 45 days from now, with phase 1 trials starting on July 7th. I can see that's not possible, but what is actually the shortest period of time for a vaccine to go from phase 1 to approval?
Phase 3 as I understand it is about testing efficacy, which is a function of N and infection rate. If you choose a sufficiently large N and happen to choose a city of high infections, I can imagine phase 3 could be completed pretty rapidly. Am I wrong?
Big difference between zero and “close” though.
With next to no tourists from overseas, freedom of movement within Australia must be really important right now, to keep the economy even vaguely functional.
Seems a bit over-ambitious to get/keep the whole country at zero if you’ve ongoing outbreaks in NSW and Victoria (two most populous states, right?)
Can they still stuff delivered off Amazon etc?
Phase 3 is primarily about efficacy but it’s also about safety. In smaller Phase 1/2 studies you’re unlikely to uncover rare, serious side effects. The type of thing that might only happen to 1 in 100 or 1 in 1000 people. Which is obviously really important when you’re developing a drug that will be given to millions.
Unless you’re deliberately infecting volunteers I don’t see how the Phase 3 study could be done as quickly as you’re suggesting. Even in a population that’s absolutely riddled with virus it would be impossible to get enough subjects exposed in such a short period of time.
Thanks. I have a couple more questions if you wouldn't mind.
- Are there two types of side effects? That is, a) side effects due to the vaccine themselves b) side effects in people who are infected given they've been vaccinated.
- Can side effects for (a) or (b) develop after many months?
If the answer to (1)(b) is "yes", it'd be very tough to do a trial rollout of a large enough N in a short enough time in the order of months.
If the answer to (2) is "yes", then increasing N beyond a point will not help and it's just a question of time.
I am wondering how some of these vaccines seem to be on track for such a fast track rollout..
https://timesofindia.indiatimes.com...ne-maker-stirs-a-row/articleshow/76778724.cms
I’m not sure I understand 1 b) but the side effects that matter most with vaccines are independent of the disease they’re supposed to prevent, if that’s what you’re asking?
There is a specific phenomenon called Antibody Dependant Enhancement which everyone is very worried about and happens when someone gets exposed to the antigen for a second time. So that complicates things. And yes, it can take a while for some side effects to get uncovered.
Basically, the timeline you describe sounds completely unrealistic!
Amazon in Australia isn’t like Amazon in the UK. Deliveries can take days.
That sucks. Saying that, they don't have it at all in my wife's country. Feels like living in the dark ages.
Wuhan style. Just missing the welders
Wenger no mates
Keeping it at zero will come at immense cost as you are virtually looking at being in and out of lockdowns for the next couple of years. What Nordics and Germany are doing is just much more sustainable and realistic long term.