Astronaut's DNA no longer matches his identical twin

Discussion in 'Current Events' started by Raoul, Mar 15, 2018.

  1. Mar 15, 2018
    #1

    Raoul Admin Staff

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    This is amazing. Interesting ramifications for a mission to mars as well.

  2. Mar 15, 2018
    #2

    Grinner Fat gutted, hairy shouldered, stinky Arse. Staff

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  3. Mar 15, 2018
    #3

    Redlambs Creator of the Caftards comics

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    'Space genes!' :lol:
  4. Mar 15, 2018
    #4

    SwansonsTache incontinent sexual deviant & German sausage lover

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    Just watched Annihilation on Netflix last night, this confirms that it was factual.
  5. Mar 15, 2018
    #5

    Grinner Fat gutted, hairy shouldered, stinky Arse. Staff

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    So he's a real space oddity?
  6. Mar 15, 2018
    #6

    harms Shining Star of Paektu Mountain Staff

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    Pretty sure that I've read it before — like a year ago or something. Although maybe it was just a theory at that point, based on his case.
  7. Mar 15, 2018
    #7

    harms Shining Star of Paektu Mountain Staff

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    Genes control to major Tom
  8. Mar 15, 2018
    #8

    Raoul Admin Staff

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    Fascinating that his telemeres got longer when he was in space. Presumably slowing down aging ?
  9. Mar 15, 2018
    #9

    Edgar Allan Pillow Ero-Sennin

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    :lol:
  10. Mar 15, 2018
    #10

    berbatrick Full Member Scout

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    Bad headline.

    His gene expression changed in response to stress - this is the classic example of how we analyse networks in bacteria too (grow them, stress them, see how the gene expression changes, dive into the details of the changed genes). It is literally exactly what should have happened. The expression mostly returned to baseline when he came back home. What also changed was the epigenetic marks on the DNA, which are known to play a role in the regulation of gene expression - this is also expected stuff.
    The use of the word "mutation" in the article seems to be misleading, nowhere else do they mention a change in DNA *sequence*.


    The part about telomeres increasing length (which has implications of lifespan and cancer (both increase)), is what is true regarding the headline, but telomeres length does change even on earth, in response to stress. Stress was thought to shorten telomeres, but the correlation was weak. There is an interesting article showing a mechanism by which stress that causes DNA damage (like UV exposure) might lengthen telomeres as a side-effect of the DNA repair machinery involved in the response to DNA damage. This could have been happening to him in space. Still, it is interesting that they got back to normal length once he got back home, and I wouldn't know how to explain that.
  11. Mar 15, 2018
    #11

    VorZakone What would Kenny G do?

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    I understood nothing of this post. :lol:
  12. Mar 15, 2018
    #12

    berbatrick Full Member Scout

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    :(
    To simplify: your genes are stored as sequences of DNA. They didn't change.
    But, individual genes can be turned on/off or low/high in response to stress. For example, if a bacteria senses food, it will turn on the genes that help it digest that food. So for this guy, in response to the stresses of space, some portion of genes got tune on or off. They mostly returned to normal when he got back to earth. A gene changing its expression like this does not mean that gene itself changed - the sequence remains the same (and when you have a child, it is the sequence that you pass on).
  13. Mar 15, 2018
    #13

    Skills Snitch

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    So is he technically still a human then (or is that a different definition)? Humans share 98% of the genes with a chimpanzee, so this guy is 5% further away.
  14. Mar 15, 2018
    #14

    BootsyCollins Full Member

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    This post is amazing. Maybe my favorite post.

    If i ever wonder about anything i will ask you. You are by far the smartest person i have ever seen.
  15. Mar 15, 2018
    #15

    berbatrick Full Member Scout

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    *blushes*
    Lol I just happen to be studying similar stuff, but thanks.
  16. Mar 15, 2018
    #16

    jojojo JoJoJoJoJoJo Staff

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    Yes, the Café can be incredible like that at times.

    Nice one berbatrick.
  17. Mar 15, 2018
    #17

    donkeyfish Full Member

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    Is there a good popular science book about epigenetics?
  18. Mar 15, 2018
    #18

    rcoobc Not as crap as eferyone thinks

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  19. Mar 15, 2018
    #19

    VeevaVee despite the protests, wears Ugg boots Scout

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    Innit. Was just about to say this.
  20. Mar 15, 2018
    #20

    jojojo JoJoJoJoJoJo Staff

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    :smirk:
  21. Mar 15, 2018
    #21

    Raoul Admin Staff

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    Way to ruin my sensational headline with facts. :rolleyes:
  22. Mar 15, 2018
    #22

    Member 5225 Guest

    Basically Wi-fi and radio waves on Earth DO feck with you! :p
  23. Mar 15, 2018
    #23

    Member 5225 Guest

    Bump the post again at awards time, I say!
  24. Mar 15, 2018
    #24

    edcunited1878 Full Member

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    Take. A. Bow. Cheers!

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