I was looking at Paulo Futre earlier this week. In retrospect it's crazy how federations don't have the long term interest of players and also their on national team in mind. Monday Koundé started a game despite the fact that he was supposed to get surgery the following day, players are selected or played despite injuries we saw that with Rashford.
For clubs you can somehow understand the importance of short term results for managers and certain football executives but most federations are filled by people that have a guaranteed long term job, almost none of them are in danger due to a single tournament. Any player that is unfit or at risk should be put aside by the federation itself.
Federations also involve a lot of money: sponsors, huge fees for friendly matches or tournaments, UEFA/FIFA prize-money, TV rights, etc.
Internacional football became a big business way before football club. Back in the days FIFA world CUP was a gold mine for broadcasters, FIFA and federations.
There should be a role on the federations to defend players interests, but unfortunatelly I fear ir would add more problems to the equation than solutions.