Amad will not play, has yet to train with the team, Pellistri has Covid, Ighalo will feature.
Other candidates for inclusion are Eric Bailly, who played four consecutive games over Christmas and New Year before missing the Carabao Cup semi-final with Manchester City on Wednesday.
Jesse Lingard could also feature. The England international has only played twice this season, and has not featured since the League Cup tie at Brighton in September, but could return against Watford, a side who were on the receiving end of one of his greatest goals back in 2017.
Ole reported no other injury concerns while speaking to the media before Saturday's game – a welcome boost ahead of a busy eight days that also includes Premier League trips to Turf Moor and Anfield, to face Burnley and Liverpool, respectively.