When they lose the House (almost certain to happen) that means an end to any chance of passing a single bill for 2 years. Anything the GOP passes in the house will be toxic and will not make it through the Senate, even if the GOP retakes it (50/50 chance), or will be vetoed if the GOP nukes the filibuster.
If the Dems had any backbone (
) they would ram everything possible during the lame duck session. Marriage protections, contraceptive protection, abortion protections, anything they can bribe/threaten Manchin/Sinema to do. They won't do this because they are cowards, but they should.