I don't think it is particularly sustainable in modern football where the onus is on fitness/running as much as it is about footballing ability. I know we have a much worse side than you so using our experience of 4-4-2 will be a bit different but you could see the clear pros and cons of the system throughout Ancelotti's tenure so far.
You absolutely need specialists in each position with clear and defined roles and it's unlike the 4-2-3-1 or other variants where one player usually has a bit of licence to roam or do what they want. I'm going to contradict myself slightly as that's what Richarlison is allowed to do in our 4-4-2 system BUT it is only due to his incredible work rate and defensive nous that he is capable of doing so. One of your forwards needs to be capable of pressing/tracking back just as much as they are involved in the attacking play. The other forward basically needs to be a dog. Scrappy, works hard, wins all aerial duels, strong, does all the dirty work in the attack - helps if they can score a bit too (DCL). The midfield is our downfall because ours can't run or create so it puts a lot of pressure on the front 2 to do so but ideally you'd have someone like Allan (who we are interested in) or Gueye who we let go that can do all the hard work in midfield and operate box-to-box. The wide men in our system tended to float inside, help the midfield out a bit but also gave space to the full-backs to create which are also very important in the system as they have to be capable of notching up a decent number of assists or chance creation (Which Digne does).
Anyway, because of all that your squad needs to be incredibly fit and of a very good level ability wise to make it sustainable and capable of winning titles, plus speciailised in their certain positions. I think you have the ability but not the players that fit that type of system. The way you play relies on a fluid attacking trio with a CAM that plays a high risk game which means you need a box-to-box midfielder in Pogba to fight for scraps in the middile/playmake aswell but also another player in the Matic mould that can cover for it in your own half. Matic/Bruno midfield two or Bruno/Pogba midfield 2 would maybe work in some games but in others you'd get shat on.