Even at this early stage, I expect Mourinho to take no risks in an away game against a team that will be pumped up & playing their first home game of the season. I'd guess we'll have a 4-3-3 to make sure we boss the midfield, Herrera being the obvious choice for the extra man coming in.
I don't think you can drop Rashford after a strong performance, and I think you need a bit of craft against a team that will sit back for some spells in the game, so I'd guess Mata or Mkhi will get the nod. Probably extra Mkhi for the pace. But the good thing is at the weekend Martial, Mata, Mkhi and Rashford all played well and there are lots of combinations of them that would be similarly good. Obviously sticks with Lukaku up front.
The back is still a bit uncertain, but I guess if Mourinho thought Jones and Blind were worth a start at the weekend, I dont suppose he'll have changed his mind after that performance.
Rashford-Lukaku-Mkhi
Pogba-Matic-Herrera
Blind-Jones-Bailly-Valencia
DDG