Spoony
The People's President
So are you admitting to being a pensioner at last?
He he. Just got lucky!
So are you admitting to being a pensioner at last?
You were doing God’s work.At a pub I used to work at we had really long lines to the cellar for some reason and my manager used to get really annoyed that I’d pour a pint or two off before I served the first customer of the day. Couldn’t get it through her head that I’d either pour it off and have a happy first customer or dont and the pint will come back our way anyway because it’ll taste like shite
Yeh well I ate my bodyweight in chocolate orange Club biscuits, so swings and roundabouts innit.A biscuit?! Pfft. In Ireland you get a half pint of Guinness. Not joking. Full of iron apparently.
English Guinness suffers for all the reasons you state but even if everything is perfect it isn't anywhere near as good as a good pint in Ireland (very drinkable mind). The water having to be chemically adjusted for hardness maybe? Eben Australian brewed Guinness is better.It’s actually fine. If you go to pubs where it’s popular. Which is most pubs these days. Used to be grim because it wasn’t very popular so the first pint would come out of the pipes all stale and rank tasting. Plus the barman usually didn’t know how to pour it.
Nowadays it’s not unusual to find pubs in Ireland with shit Guinness. Full of hipsters drinking craft ales. Although when you go to a pub that pours a good pint it’s very very good.
God I miss good pints of Guinness. Feck you, covid
Yes. No excuse for stale beer or dirty lines.You were doing God’s work.
beer is a medicineYou enter a thread about a medicine and the british-irish are talking about beer...
And a health food and therapy. And a hobby.beer is a medicine
That seems accurate.And a health food and therapy. And a hobby.
First real world preliminary study has it much lower than anticipated, at 33%.I've probably been reading too many tabloids, but I though the Pfizer one was up to 91 % effective after one dose.
That is a genius idea.So UK is distributing vaccines injected into beer?
There is an extensive study with 40.000 subjects that tested each vaccine approved before rolling out. There are clear instructions on how it should be administrated. But the UK decided not to administrate as the manufacturer said it should be implemented. So is not hit and miss, is just the UK gamblingDoes anyone know what these vaccines do or have they just been approved out of desperation and then hope for the best . It all seems very hit and miss . Chopping and changing when to give the 2nd dose and what the actual protection will be. It is hard to know what to believe when people are desperate to get back to some level of normality socially and economically . I hope the scientists haven't got it wrong .
We know very well what they do. The vaccines are safe and effective or very effective. Like all non-sterilising vaccines (the vast majority in all cases) we won't know how much this will reduce the R value and/or the transmission but it is looking very optimistic.Does anyone know what these vaccines do or have they just been approved out of desperation and then hope for the best.
The gap between doses isn't anything to do with scientists getting it right or wrong but rather a public health response to the pandemic. Ideally you stick to the gap that was tested during trials but in this unprecedented case they are hoping that giving as many people as possible the first shot will on average reduce transmission as compare to giving a reduced number of people 2 shots on schedule. As a former scientist (biologist not immunologist) my instinct would be to go as fast as possible with the approved gap between but I can see the advantage of maybe getting 60/70% effectiveness for nearly twice as many people vs 90+% for the lesser number. I guess the danger is we don't really know what leaving a bigger gap will do to the overall effectiveness (hopefully nothing).It all seems very hit and miss . Chopping and changing when to give the 2nd dose and what the actual protection will be. It is hard to know what to believe when people are desperate to get back to some level of normality socially and economically . I hope the scientists haven't got it wrong .
What about the risk of the virus mutating adapting to the vaccine that is not as as strong as possible with 2 shots?We know very well what they do. The vaccines are safe and effective or very effective. Like all non-sterilising vaccines (the vast majority in all cases) we won't know how much this will reduce the R value and/or the transmission but it is looking very optimistic.
The gap between doses isn't anything to do with scientists getting it right or wrong but rather a public health response to the pandemic. Ideally you stick to the gap that was tested during trials but in this unprecedented case they are hoping that giving as many people as possible the first shot will on average reduce transmission as compare to giving a reduced number of people 2 shots on schedule. As a former scientist (biologist not immunologist) my instinct would be to go as fast as possible with the approved gap between but I can see the advantage of maybe getting 60/70% effectiveness for nearly twice as many people vs 90+% for the lesser number. I guess the danger is we don't really know what leaving a bigger gap will do to the overall effectiveness (hopefully nothing).
Vaccination in general risks viral mutation. Traditionally the main risk has been thought to be that the rapid eradication of a virus will leave an ecological niche to be be filled by other pathogens. I'm not sure if that has ever actually happened but it was (and maybe still is) considered the main risk. The other big risk is that you eradicate all of the virus expect a very few variants/strains that are adapted to be least effectively dealt with by the vaccine. So in this case the few left might explode, creating an new wave but one that one or more vaccines don't deal with as well (or in the worst case at all). However, less effective vaccines (or a roll out that cause the vaccines to be less effective) actually place less evolutionary pressure on the virus, but at the cost of there being more infections and therefore more opportunity for "normal" evolution of the virus. Six of one and half a dozen of another maybe? I'm not an expert so I'd be just guessing which is a bigger risk but my instinct is that the risk of the delay is less than the risk of almost half as many people getting partial immunity (at a level that would have seen a vaccine be approved if that was its maximum effectiveness).What about the risk of the virus mutating adapting to the vaccine that is not as as strong as possible with 2 shots?
Sorry to hear that. I hope your Grandma pulls through. Lets hope the vaccine was given early enough that is at least lessens the severity of her symptoms.This time last year I had four relatively healthy albeit aging grandparents. We lost my Grandpa to Covid in April. My remaining grandparents had the vaccine last week but one of my grandma's has now tested positive and is back in hospital. I fear the worst as she is 90 years old. feck this disease
Thanks for the extensive explanation. Will see how it pans out and lets hope the rich countries share their extra vaccinations with the poorest on moral grounds and as well for global safetyVaccination in general risks viral mutation. Traditionally the main risk has been thought to be that the rapid eradication of a virus will leave an ecological niche to be be filled by other pathogens. I'm not sure if that has ever actually happened but it was (and maybe still is) considered the main risk. The other big risk is that you eradicate all of the virus expect a very few variants/strains that are adapted to be least effectively dealt with by the vaccine. So in this case the few left might explode, creating an new wave but one that one or more vaccines don't deal with as well (or in the worst case at all). However, less effective vaccines (or a roll out that cause the vaccines to be less effective) actually place less evolutionary pressure on the virus, but at the cost of there being more infections and therefore more opportunity for "normal" evolution of the virus. Six of one and half a dozen of another maybe? I'm not an expert so I'd be just guessing which is a bigger risk but my instinct is that the risk of the delay is less than the risk of almost half as many people getting partial immunity (at a level that would have seen a vaccine be approved if that was its maximum effectiveness).
The main hope though is that for a virus to mutate so much that a vaccine didn't work at all the whole spike would need to change (as vaccines don't work on just one bit) and the chances of that happening, and the virus still being highly infectious to humans is very small (but not impossible). My guess is that the faster we can immunise as close to 100% of people as possible, in as many countries as possible, in whatever way we can the better and if the virus mutates then so be it. I'm not sure what we can do about that. Any choice has a risk attached.
Bear in mind I was a biologist/evolutionary ecologist in a previous life so was OK with biological evolution, but I don't know any more than I've read this year about viral evolution, which is significantly different (but with lots of commonalities). I could be off the mark quite easily.Thanks for the extensive explanation. Will see how it pans out and lets hope the rich countries share their extra vaccinations with the poorest on moral grounds and as well for global safety
It is our best interests to get everyone vaccinated. Once Australia gets itself vaccinated I'd hope we keep producing the Oxford vaccine to help our neighbors in the Pacific and further away. Sounds like a sensible investment if nothing else to me. Not holding my breath mind.Thanks for the extensive explanation. Will see how it pans out and lets hope the rich countries share their extra vaccinations with the poorest on moral grounds and as well for global safety
I don't think the WHO have been as bad as they have been portrayed.The heavily corrupted WHO, aka the major cause of this pandemic, talks about moral failure. What a joke.
https://www.bbc.com/news/world-55709428
Sorry to hear that fella. My grandmother is of a similar age with an impressive collection of underlying health conditions yet still managed to battle the fecker away. So hang in there for yours! Hopefully the vaccine gives her a boost to fight it too.This time last year I had four relatively healthy albeit aging grandparents. We lost my Grandpa to Covid in April. My remaining grandparents had the vaccine last week but one of my grandma's has now tested positive and is back in hospital. I fear the worst as she is 90 years old. feck this disease
I have analyzed the wrongdoings of China and WHO in another thread (scroll above for more details). They are the major culprits for the pandemic and they have no right to complain.I don't think the WHO have been as bad as they have been portrayed.
And they aren't wrong on this point either.
Well that’s quite a comprehensive analysis. Thanks for sharing.I have analyzed the wrongdoings of China and WHO in another thread (scroll above for more details). They are the major culprits for the pandemic and they have no right to complain.
https://www.redcafe.net/threads/sar...oil-hat-silliness-please.452816/post-26536480
Thanks. I understand many of you may be frustrated about how your government deals with the pandemic (and yes they could have done a lot better), but let's not forget the one who causes the damage always shoulders a larger responsibility than those who fail to limit the damage.Well that’s quite a comprehensive analysis. Thanks for sharing.
They have every right to say something about the equitable distribution of vaccines. Doubly so as they are right.I have analyzed the wrongdoings of China and WHO in another thread (scroll above for more details). They are the major culprits for the pandemic and they have no right to complain.
https://www.redcafe.net/threads/sar...oil-hat-silliness-please.452816/post-26536480
Oh, sorry I was being sarcastic. Maybe that didn’t come across well enough.Thanks. I understand many of you may be frustrated about how your government deals with the pandemic (and yes they could have done a lot better), but let's not forget the one who causes the damage always shoulders a larger responsibility than those who fail to limit the damage.
Why don't they say anything but their total failure in preventing this pandemic, leading to the inevitable consequence that poorer regions suffer more? Wealth, food, resources etc are all distributed unequally in the world and I don't see vaccine as an exception. It is not ideal but it is something you have to cope with, especially when you are the major culprit for the mess in the first place. Plus, WHO received a lump sum of donation from China (for covering up), they could have spent it on vaccines if they care so much.They have every right to say something about the equitable distribution of vaccines. Doubly so as they are right.
The are an integral part of Covax which is trying to supply vaccines more equitably and spending huge sums on it. So again an unfair criticism.Why don't they say anything but their total failure in preventing this pandemic, leading to the inevitable consequence that poorer regions suffer more? Wealth, food, resources etc are all distributed unequally in the world and I don't see vaccine as an exception. It is not ideal but it is something you have to cope with, especially when you are the major culprit for the mess in the first place. Plus, WHO received a lump sum of donation from China (for covering up), they could have spent it on vaccines if they care so much.
He was actually saying that you hadn't analysed really - more just stated a dislike.Thanks. I understand many of you may be frustrated about how your government deals with the pandemic (and yes they could have done a lot better), but let's not forget the one who causes the damage always shoulders a larger responsibility than those who fail to limit the damage.
Think your tinfoil is showing. Human to human transmission was not going to be identified day one in Wuhan for obvious reasons.Why don't they say anything but their total failure in preventing this pandemic, leading to the inevitable consequence that poorer regions suffer more? Wealth, food, resources etc are all distributed unequally in the world and I don't see vaccine as an exception. It is not ideal but it is something you have to cope with, especially when you are the major culprit for the mess in the first place. Plus, WHO received a lump sum of donation from China (for covering up), they could have spent it on vaccines if they care so much.
Yes, and richer regions have also played their parts in donating to COVAX. After this point, it's WHO's responsibility to make good use of the fund and distribute vaccines as equal as possible. Pointing the fingers at richer regions is merely shirking their responsibility.The are an integral part of Covax which is trying to supply vaccines more equitably and spending huge sums on it. So again an unfair criticism.
There was strong evidence of human-to-human transmission as early as mid January. WHO chose to ignore the threat and time has proven who is right.Think your tinfoil is showing. Human to human transmission was not going to be identified day one in Wuhan for obvious reasons.
By the time they identified it was spreading human to human the world could have shut down flights but it would already have been too late. No one was stopping this spreading globally.
I actually suspect if this had started in any western country it would have been much worse as we wouldn't have locked down like Wuhan. I doubt we'd even have any restrictions within the first two months.