How is it not significant? If we are choosing between these two players, I think their best versions logically come into play.
For me, the current Messi is the best Messi, while the current Ronaldo is not the best Ronaldo, as I prefer him from his early Madrid days.
How can Ronaldo be better than Messi if his current version is inferior to the one that won less? You can see how this makes the Ronaldo argument problematic, as his advocates will always turn to the champions league titles as evidence of his superiority, though it seems a younger version of him was better without all that success.