SARS CoV-2 coronavirus / Covid-19 (No tin foil hat silliness please)

JPRouve

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I think the gist was that the symptoms disappeared but the virus was still present or something.
Here are 2 reddit threads discussing it:

1. 2.
From what I have read, we don't really know. That's why I believe that it's best to stick to the way the symptoms evolved when someone ask that type of question, the rest is pure speculation.
 

fergieisold

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I agree, a lot of older people I know are feeling very upset about it and that’s on top of the fear they have. This is not a good time to feel old and vulnerable.
but they are statistics just as we younger people are. Unfortunately they are on the wrong end.

This is insane. UK is signing a Holocaust on its own people. To make things even worse, no one is able to answer any of these questions:

1) Are we sure that the disease won’t return?

2) Are we sure that the fatality rate won’t be higher than 1-3% (it is currently 7% in Italy)?

3) Are we sure that the virus won’t mutate on something more deadly?

4) Are we sure that there won’t be long-term consequences (in worst case HIV-like) for the survivals?

No one has any clue to answer any of these questions, but somehow they’re ok with 50 million people catching it within the year.

This is beyond madness!
calm the feck down. Fatality rate is likely to be below 0.5 % overall.

I think the gist was that the symptoms disappeared but the virus was still present or something.
Here are 2 reddit threads discussing it:

1. 2.
re exposed to high levels when immunity not built
 

Revan

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And how do you propose to shutdown society for the 18 months its touted to get a vaccine into circulation? I mean in economic and social terms?
China is doing it, and their entire economy is production based. This could be easily the equivalent of WW2, I think we can sustain some economic hardships.
 

marktan

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I am surrounded by lunatics. One side thinks this is only a flu and the other ones are buying food for a year and are predicting the end of the world. People are so irrational.
Which ones the correct one?
 

Revan

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You’d be a pretty shit Hitler if this was your means of genocide.

1) The virus is likely systemic now. It isn’t going anywhere unless a miracle is found. That’s why we need a vaccine.

2) Yeah, we’re certain. Higher mortality rates will only occur if the health system collapses and those who develop complications don’t get the timely interventions they need. Most will self treat and brush it off, or be quite ill but still recover.

3) We don’t know, but we’re going to have to deal with that problem anyway. We already vaccinate against mutating viruses annually.

4) The stigma of being HIV+ is far worse than the reality of living with it, provided you follow treatment. People live a full life nowadays. This is a completely different type of disease regardless.
2) And how does the system will be able to cope if 45 million people get infected this year? Model it in any distribution you might think of, it is literally impossible for it to happen.

Which is why the mortality rate will be higher.
 

TMDaines

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China is doing it, and their entire economy is production based. This could be easily the equivalent of WW2, I think we can sustain some economic hardships.
Have you seen the poverty in China?
 

sullydnl

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I still don't understand this logic.

Let's say he's right - after all, he's a professor - and herd immunity is the only way now. But what until we achieve that? Simply letting the virus explode all over the health systems of various countries will have devastating consequences and a staggering death count. Surely, surely, measures that delay that explosion and grant health services time to prepare, to amass more resources and such are necessary and good?

Because this UK idea seems to be simply that the most vulnerable should have the decency to die quickly, the rest should preferably not seek medical attention but wait until it passes. It's all-round weird.
That's kinda what's confusing me about their approach too.

The countries who are attempting to minimize the spread of the disease as much as possible face a real risk of being overwhelmed. So how does a country which isn't attempting to minimize the spread of the disease to the same degree avoid being overwhelmed?
 

Kill 'em all

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This is insane. UK is signing a Holocaust on its own people. To make things even worse, no one is able to answer any of these questions:

1) Are we sure that the disease won’t return?

2) Are we sure that the fatality rate won’t be higher than 1-3% (it is currently 7% in Italy)?

3) Are we sure that the virus won’t mutate on something more deadly?

4) Are we sure that there won’t be long-term consequences (in worst case HIV-like) for the survivals?

No one has any clue to answer any of these questions, but somehow they’re ok with 50 million people catching it within the year.

This is beyond madness!
If you calculate the fatality rate by means of the amount dead and the total confirmed infected cases, you are using a very flawed assumption that the government knows of every infected case. The infected portion of the population that doesn't get severe symptoms or is completely asymptomatic to the infection will never be in that known cases amount the government is reporting.
 

Paxi

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This is insane. UK is signing a Holocaust on its own people. To make things even worse, no one is able to answer any of these questions:

1) Are we sure that the disease won’t return?

2) Are we sure that the fatality rate won’t be higher than 1-3% (it is currently 7% in Italy)?

3) Are we sure that the virus won’t mutate on something more deadly?

4) Are we sure that there won’t be long-term consequences (in worst case HIV-like) for the survivals?

No one has any clue to answer any of these questions, but somehow they’re ok with 50 million people catching it within the year.

This is beyond madness!
Well I think scientists are expecting this disease to become endemic but by then we will have a vaccine and antibodies from being naturally exposed to it.

I'm fearing the CFR will be higher in UK. I think Italy has more ICU beds than UK and CFR is 5.4% of the known cases.

I think it would be actually better for the virus to mutate into something more deadly paradoxically as it doesn't have the ability to transmit as a low mortality rate strain. Someone can correct me if I'm wrong on that.

And from what I read there is not enough data to know if it causes any permanent damage to the immune system or lungs etc.

Anyway I'm sure someone like @berbatrick @Pogue Mahone or @Arruda can answer in greater detail and much more eloquently.
 

Conor

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Irish government has created a field hospital in a football stadium in Dublin. Surprisingly proactive.
 

Fully Fledged

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His curves not being correct was in the context of him using a normal distribution, which is not necessarily the case for infections. However, under some assumptions when independent random variables are added, they tend to converge towards a normal distribution. So, while his curves are not correct, they can serve as modeling.

However, his point is totally correct. If you have millions of sick people at the same time, but you can offer ventilators to only a few thousand, then a lot of sick people will die (with 5% of infected people needing oxygen ventilators).

Timothy Gowers (one of the most famous respected mathematicians in the world) came to the same conclusions.
I'm not a doctor but this seems obvious to me. I can't see how other people can't see it.
 

Revan

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According to epidemiologists in Belgium, a new virus will never mutate into something more deadly since it’s basically “a teenage virus which hasn’t learned to live with its human yet”. If it would become more deadly, it would kill its carrier thus be ineffective as it actually needs its human carrier to survive itself. Or something like that. Anyway according to multiple experts here - if it’ll mutate it’ll be for the better.

I’m currently in Jordan with a return flight to Amsterdam scheduled tomorrow night. Jordan has suspended all air travel as from Tuesday so I’m really hoping my flight goes through or I could be stuck here for a very long time which I really don’t fancy right now. Just wanna be fecking home again even if it’s way worse there atm.
In general yes, they should mutate to less deadly versions. In general, also a reinfection should be just a mild version of the sickness.

But it is not always the case. The second wave of Spanish flu was more deadly than the first one. The second time someone gets infected from the dengue fever, it is much worse than the first time.

So my point is, we do not know. It might be that this will have a low mutation rate and even when it mutates it will be less deadly so good news. There is some chance though that it might get worse. So, why some think that the most brutal scenario is the best one, when we know so little of it.

Good luck for your flight! I am half tempted to leave my job in the US and return to Europe. Scared that when the economy goes down, I might suddenly be without a job, a house, and an insurance, in a foreign country, with flights to Europe being banned.
 

Classical Mechanic

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China is doing it, and their entire economy is production based. This could be easily the equivalent of WW2, I think we can sustain some economic hardships.
It's a totalitarian regime and they've been doing it 2 months! Do you think that they'll care if the poorer citizens are starving to death in a longer term scenario or do you think they'll just dispose of the bodies on the quiet? WW2 featured massive crimes by the state on their own people, Enigma, for example. You're basically advocating for the same, if not worse, than the British approach to this virus with that comment through sacrificial lambs.
 

Fully Fledged

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JPRouve

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There is none.
And the worst part is that you are already busy, you already have patients in critical conditions that needs your attention and there will be people that will be in critical conditions for reasons none related to Covid-19. It's not simply illogical, it's just staggeringly stupid.
 

Ekkie Thump

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If you calculate the fatality rate by means of the amount dead and the total confirmed infected cases, you are using a very flawed assumption that the government knows of every infected case. The infected portion of the population that doesn't get severe symptoms or is completely asymptomatic to the infection will never be in that known cases amount the government is reporting.
You also don't know the final amount of dead. Both the numerator and denominator are variable.
 

OutlawGER

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In german paper its been reported that Iran made something like 7,5mio tests in the past few days and the result was 175,000 positive on Corona.
 

RedSky

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A silicon valley entrepreneur who has written a book about Star Wars, no less.
To be fair, I checked myself and his company does at least produce computer models on spreads of diseases. It's not like they pulled a random person from the street to talk about it. He's therefore got a pretty decent idea no doubt having constructed several different models on how it could (the models could easily be wrong) spread. I.E. He's played a feck ton of Pandemic the board game.
 

sport2793

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Which ones the correct one?
The former more than the latter. The flu actually kills more people per year than folks realize. It's just that we usually have a good vaccine against it. COVID 19 is a novel virus with no vaccine against it = more infectious.
 

sebsheep

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When I see this I can only assume that they either A. Run a business or B. Are hedging their bets and intend to sell it in a few weeks time.
Would you be buying from a supermarket if you needed it for a business though? Seems like you'd have such a low profit margin on it.
 

Revan

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If you calculate the fatality rate by means of the amount dead and the total confirmed infected cases, you are using a very flawed assumption that the government knows of every infected case. The infected portion of the population that doesn't get severe symptoms or is completely asymptomatic to the infection will never be in that known cases amount the government is reporting.
I know that. At the same time, there are many cases which yet we do not know their epilogue, so the number of deaths might increase. There are ways of having better estimates, it looks like in Italy and Iran (overwhelmed but still functional medical system) it is converging around 4%. That is very bad.

Imagine the numbers with a totally non functioning medical system (which is gonna happe
 

Arruda

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And the worst part is that you are already busy, you already have patients in critical conditions that needs your attention and there will people that will be in critical conditions for reasons none related to Covid-19. It's not simply illogical, it's just staggeringly stupid.
Only villains or ignorants can possibly think there is any logic in that.
 

Skills

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In german paper its been reported that Iran made something like 7,5mio tests in the past few days and the result was 175,000 positive on Corona.
The UK, USA & Iran. 3 countries ran by shithouses, all headed for the same fate.
 

Rado_N

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All these people banging on about “more people die of the common cold/flu” seem to be completely ignoring the rate of deaths and the speed of the spread which are the concerning things.
 

Paxi

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That's kinda what's confusing me about their approach too.

The countries who are attempting to minimize the spread of the disease as much as possible face a real risk of being overwhelmed. So how does a country which isn't attempting to minimize the spread of the disease to the same degree avoid being overwhelmed?
Which is why I don't get this thing about time. Surely the earlier the better. I understand that people may not want to hold curfews and will break quarantine but Italy so far is doing fairly well in that sence. Surely every proactive step is a right one? I can understand holding schools off as long as possible and essential services but letting the country just crack on as normal is quite frankly bizarre in my opinion. If not for CHO and Arteta Arteta we'd still have fixtures with hundreds of thousands attendees at games. I can't wrap my head around it. Especially after every other country in Europe is taking a different approach. This Sir Patrick Vallance is either an absolute genius or he will literally e hung drawn and quartered when this all over.
 

redshaw

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This is a break down of the UK govt approach in simple terms by someone qualified.

Professor Ian Donald
@iandonald_psych

Psychologist:Social, & Environmental research, & behavioural factors in Anti-Microbial Resistance. Emeritus Professor, University of Liverpool. Typos all my own


The idea that essentially the WHO approach is reactive and only delaying an inevitable storm at a greater social and economic cost overall.
Problem here is he's filling in the blanks to what he thinks might be going on, would be good to get clear info from the Tories and stop the rampant speculation. I expect UK will follow suit with Spain and France when we get to those numbers thereabouts. The herd immunity will take out so many older people and those with comprised health of all ages and would need very specific instructions and secondary help that isn't there for those people to stay away from the healthy majority while they get infected. Too many won't be responsible enough or dedicated enough. NHS would be quickly overwhelmed. This would also need a quick turnaround of the healthy getting infected and recovering.

Should other countries get passed this with 3000 dead like China and UK has substantially more I think public hanging and stoning would be brought back for the whole party.

Feel like sending my mum to Hubei for 3 months, probably the safest place right now.
 

Stactix

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Well I think scientists are expecting this disease to become endemic but by then we will have a vaccine and antibodies from being naturally exposed to it.

I'm fearing the CFR will be higher in UK. I think Italy has more ICU beds than UK and CFR is 5.4% of the known cases.

I think it would be actually better for the virus to mutate into something more deadly paradoxically as it doesn't have the ability to transmit as a low mortality rate strain. Someone can correct me if I'm wrong on that.

And from what I read there is not enough data to know if it causes any permanent damage to the immune system or lungs etc.

Anyway I'm sure someone like @berbatrick @Pogue Mahone or @Arruda can answer in greater detail and much more eloquently.
Per 100k there are 6.6 icu beds in UK, though not sure how they're spread? Couple that with 80-90% already been in use I would bet?

Around double that in Italy and 29.2 in Germany

the NHS is fecking struggling as it is.

I'm personally thinking something akin to Lombardy will happen in the UK, Like Cheltenham suddenly gets a surge of cases or Liverpool or Cornwall and completely overwhelms the local system.

I think with this strategy, doubld the resources still royally fecked. The thing people seem to forget is the NHS is severely understaffed and resourced as it is and every other problem still needs to be dealt with. That isn't put on hold:/ A system with cracks breaking through the seams has to now deal with a pandemic, with a government taking a massive fecking gamble when countries that are coping with this have gone completely different ways.
There is no evidence to suggest this builds immunity
There is no way the UK is prepared for this.
 

Ekkie Thump

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I know that. At the same time, there are many cases which yet we do not know their epilogue, so the number of deaths might increase. There are ways of having better estimates, it looks like in Italy and Iran (overwhelmed but still functional medical system) it is converging around 4%. That is very bad.

Imagine the numbers with a totally non functioning medical system (which is gonna happe
The best gauge we're gonna get in the short term for the death rate in a fully functional advanced healthcare system is from the Diamond Princess.