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SARS CoV-2 coronavirus / Covid-19 (No tin foil hat silliness please)

Don't Kill Bill

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This is something I haven’t considered. Anyone know how possible/likely it is that while the vaccine might not build a big enough immune response to hold the virus back completely, it could produce enough of a response to kick start the fight when it does take hold.
These are the early results but if I remember correctly no one on the vaccine (12500 people) was hospitalized even if they did catch Covid. It would be a huge bonus if it holds true and the numbers are suggesting it will but there is still so much we don't understand about the disease.

If you take the vaccine and then don't die of covid even if you catch it, that might be this pandemic sorted in terms of the economic and social destruction. Tantalizingly close but too early for the cigar.
 

Rajma

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Feck, my mum (healthcare emergency worker at A&E) was treating a women on Friday who was displaying symptoms such as dizziness, weakness, vomiting that you can hardly identify with Covid (no temperature, shortness of breath, body aches, coughing). Today she got a call from contact tracing center telling her that patient had Covid and she now has to self-isolate. It's annoying as it was her last shit after she finally decided to call it a day. Now I'm really worried for her developing any symptoms as she obviously in her 50s and has asthma/hypertension and in general is prone to not having it easy once she caches a bug/flu. She's obviously brushing it off but it's very stressful right now for me given how awful/deadly this thing can be. With these vaccines around the corner as well...
 

DomesticTadpole

Doom-monger obsessed with Herrera & the M.E.N.
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Feck, my mum (healthcare emergency worker at A&E) was treating a women on Friday who was displaying symptoms such as dizziness, weakness, vomiting that you can hardly identify with Covid (no temperature, shortness of breath, body aches, coughing). Today she got a call from contact tracing center telling her that patient had Covid and she now has to self-isolate. It's annoying as it was her last shit after she finally decided to call it a day. Now I'm really worried for her developing any symptoms as she obviously in her 50s and has asthma/hypertension and in general is prone to not having it easy once she caches a bug/flu. She's obviously brushing it off but it's very stressful right now for me given how awful/deadly this thing can be. With these vaccines around the corner as well...
Hope your mum gets well soon.
 

United Hobbit

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Has he just given up with any restrictions?!

Are the cases even dropping sufficient enough to stop lockdown? It hasn't felt like lockdown here the roads have been as awful as ever
 

sammsky1

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Not really. No one who took the vaccine died of Covid 19. The trial varied doses and discovered that using a half dose then a full dose gave 90% of people protection. They will make 2 billion doses next year and you don't have to store it at extremely low temperatures.

It is in fact brilliant news probably the best we have had in the last 10 months. If please, please, please it holds up to scrutiny of the regulating body.
After taking a few hours to read up, it seems you are right. But vast majority wont have the inclination to do so and many also wont understand complex statistical data.

They made a huge cock up in communicating these results to a level that disinterested anti vaxxers would understand; that should have been the headline, with all the more nuanced stuff in the report. Massive own goal messing up some brilliant passionate and groundbreaking science.
 

sammsky1

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Has he just given up with any restrictions?!

Are the cases even dropping sufficient enough to stop lockdown? It hasn't felt like lockdown here the roads have been as awful as ever
Just got back from our Tesco Superstore: Was jam packed at 4pm on a Monday!
 

United Hobbit

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Just got back from our Tesco Superstore: Was jam packed at 4pm on a Monday!
Exactly, maybe its full of those that would have been horrified Christmas was potentially cancelled. The pressure that was being put on to allow Christmas didn't help i don't think, I thought they had the support bubble rule so its not like they were making people spend it alone.

I'd have accepted not seeing my family over Xmas if it was a rule as I'd rather They didn't catch Covid...

Was not impressed as my partners went round his parents last week even though they aren't alone... his family seem to think they're immune to the virus his brother has been Bragging how he hasn't been wearing a mask and would lie and say he was exempt if asked. I hate wearing the things but I wear them because there's a reason for it...
 

F-Red

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They made a huge cock up in communicating these results to a level that disinterested anti vaxxers would understand; that should have been the headline, with all the more nuanced stuff in the report. Massive own goal messing up some brilliant passionate and groundbreaking science.
I don't know how else they could have communicated it, but as a broad brush headline the BBC reported it as:

I don't know how else it could be interpreted? Unless 70% from the first dose (which is higher than some flu jabs) is considered a failure?
 

Wibble

In Gadus Speramus
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A friend of mine is supposed to start uni in Melbourne in March. Do you reckon Australia will open their international borders by then?
Hard to know. Quarantine hotel capacity is very limited but we will also want to let International students back ASAP as the Uni sector has been hit hard by the loss of income.
 

F-Red

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Yeah right, have you ever been Christmas shopping :lol:

Being outdoors and socially distanced is safer than being inside a shop
Mixing with different people less than 15 minutes, compared to 90 minutes next to someone? Come on, dwell time has been discussed a number of times (as early back as the start of the pandemic) in this thread.

With all the measures that retail have put in place (Coverings/Distancing/Numbers in store), the data on case rates would tend to back this up. The issue has always been household mixing. However every time there's an announcement the same comments of "Why can I do X, when I can't do Y" get rolled out.
 

Berbaclass

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Mixing with different people less than 15 minutes, compared to 90 minutes next to someone? Come on, dwell time has been discussed a number of times (as early back as the start of the pandemic) in this thread.

With all the measures that retail have put in place (Coverings/Distancing/Numbers in store), the data on case rates would tend to back this up. The issue has always been household mixing. However every time there's an announcement the same comments of "Why can I do X, when I can't do Y" get rolled out.
You won’t be directly sat next to anybody in a stadium. It will be distanced. So you’re not sitting next to random people for 90 minutes are you.
 

F-Red

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You won’t be directly sat next to anybody in a stadium. It will be distanced. So you’re not sitting next to random people for 90 minutes are you.
The Northern Ireland vs Slovakia game wasn't exactly a shining example of this.
 

sammsky1

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I don't know how else they could have communicated it, but as a broad brush headline the BBC reported it as:

I don't know how else it could be interpreted? Unless 70% from the first dose (which is higher than some flu jabs) is considered a failure?
The whole world heard 95% and 90% in last 2 weeks. Whatever the dosage nuances are, that's the benchmark most are remembering.
 
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F-Red

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The game where they made them all go through a disinfection pod?
You mean the security theatre?

There's a huge amount of security theatre going on - for some reason sports teams in particular seem to be keen on running through sprays of disinfectant, and there's been people wandering around spraying corner flags, and it's all probably useless.

This was a particularly strong example:
 

sammsky1

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How should they have communicated it then?
IMO, they should have stated something like "Oxford trial demonstrates 90% success in certain trials and 70+% as an average of various levels of doses tests conducted" or words to that effect.
 

sammsky1

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Airline to demand proof of vaccination from passengers

Australian airline Qantas has suspended almost all overseas flights until mid-2021
Passengers will have to prove they have been vaccinated against Covid-19 before boarding an international flight with Qantas, the Australian airline’s chief executive has said.
Alan Joyce told Australia's Channel 9 that the airline was “looking at changing our terms and conditions” as several vaccines await final approval.
“We will ask people to have a vaccination before they get on the aircraft. Certainly, for international visitors coming out and people leaving the country we think that's a necessity," Joyce said.
He said proof of Covid-19 vaccinations may become a “common theme” across the industry.
“What we’re looking at is how you can have a vaccination passport, an electronic version of it that certifies what the vaccine is and whether it’s acceptable to the country you’re traveling to,” he said.
Qantas has suspended almost all overseas flights until the middle of 2021, and does not expect to resume full service until a Covid vaccine becomes available.
 

LARulz

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So currently we are not allowed to fly out the UK unless it is for work, emergency etc.

What's the situation on flying out like from December 2nd?
 

Berbaclass

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You mean the security theatre?
Since when has disinfecting things been a waste of time? Obviously the virus is inside you, we all still use hand sanitiser though because its good practice. You can call it 'security theatre' or whatever you want but it's just an example of an extra precaution being taken at a football match that isn't in retail environments.
 

F-Red

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So currently we are not allowed to fly out the UK unless it is for work, emergency etc.

What's the situation on flying out like from December 2nd?
I think it'll revert back to the tier system approach that we saw prior to the November 5th restrictions, so air travel most likely will resume.
 

Berbaclass

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I trust the judgement of Prof Noakes, who specialises in infection transmission, when she says it's a terrible idea.
If you go through one of those pods with your eyes open and breathing in disinfectant then you're a moron.

Doesn't make the implementation or function of them necessary a bad idea.
 

Buster15

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Goodness me. In the PM briefing, NHS Test and Trace funding for 2021 is £22bn!!
Equivalent to 20% of the whole annual NHS budget.
Eyewatering sums of money.
 

lynchie

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If you go through one of those pods with your eyes open and breathing in disinfectant then you're a moron.

Doesn't make the implementation or function of them necessary a bad idea.
What exactly do you think dousing yourself in disinfectant achieves then?
 

Jacko21

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I've been limiting my social contacts since March and the hospital remains the only place I've visited indoors, so not about to throw to caution to the wind for the sake of Christmas - particularly will a vaccine in sight.

Only way I envisage a 'normal' Christmas Day would be for those I usually spend it with to isolate in advance and ideally to get a test (if they're made available).
 

giggs-beckham

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the 5m is just for the moderna one. they've ordered 100m of the Oxford, 60m of the Psizer one, etc
This is what it said on the radio. So why can't we give it to everyone, unless it just takes a long time to make it for that many people.
 

F-Red

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This is what it said on the radio. So why can't we give it to everyone, unless it just takes a long time to make it for that many people.
It's a bit of a challenge with manufacturing and distribution. The Moderna and Pfizer vaccines require two dosages around 15 days apart, and stored at -80 degrees, distributing it in that condition globally is a challenge as cold storage facilities exist, but the challenge of that storage conditions at the community level is somewhat limited, with the risk that the vaccine disintegrates at higher temperatures and a higher proportion of wastage potentially.

Combine that with the raw materials to power those conditions (dry ice that needs to be replenished every 5 days for a max of 15 days) and the raw materials for the vaccines themselves. The AstraZeneca/Oxford vaccine doesn't require the extreme storage conditions, but requires two doses, and arguably will be the more widely distributed vaccine due to it's far cheaper cost and accessibility.

So technically vaccinating everyone in the world would require more than 15 billion vaccine doses, and that doesn’t allow for vaccine's that are spoiled, broken or end up lost in the back of a freezer. Of course we wouldn't have to vaccinate everyone in order to stop transmission, so the figure could and probably will be lower.

It'll be phased as the production yield comes up to speed, hence why we're having a tiered approach of the most vulnerable people & front line workers being the priority. Looking at the data as long as you get to a level of 60+ having the vaccine then it addresses a large number of the demographics which are having the worst reactions to the virus.
 

giggs-beckham

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It's a bit of a challenge with manufacturing and distribution. The Moderna and Pfizer vaccines require two dosages around 15 days apart, and stored at -80 degrees, distributing it in that condition globally is a challenge as cold storage facilities exist, but the challenge of that storage conditions at the community level is somewhat limited, with the risk that the vaccine disintegrates at higher temperatures and a higher proportion of wastage potentially.

Combine that with the raw materials to power those conditions (dry ice that needs to be replenished every 5 days for a max of 15 days) and the raw materials for the vaccines themselves. The AstraZeneca/Oxford vaccine doesn't require the extreme storage conditions, but requires two doses, and arguably will be the more widely distributed vaccine due to it's far cheaper cost and accessibility.

So technically vaccinating everyone in the world would require more than 15 billion vaccine doses, and that doesn’t allow for vaccine's that are spoiled, broken or end up lost in the back of a freezer. Of course we wouldn't have to vaccinate everyone in order to stop transmission, so the figure could and probably will be lower.

It'll be phased as the production yield comes up to speed, hence why we're having a tiered approach of the most vulnerable people & front line workers being the priority. Looking at the data as long as you get to a level of 60+ having the vaccine then it addresses a large number of the demographics which are having the worst reactions to the virus.
Excellent thank you. Why aren't we focusing in the short term, in terms of order numbers on the Oxford vaccine as it doesn't have the storage issues for example.