From what we saw in preseason, Mainoo was expected to get quite a lot of game time, and Amad also would have considering his position is one we're struggling in massively.
The issue is that our unavailable players are clustered in certain positions, so rather than just bringing in our 2nd choice in a few positions we're having to go down to like 4th choice or players out of position. Left back, right wing and centre back for a while have been utterly devastated. Striker as well at the beginning of the season but that's somewhat self-inflicted since we've only got Hojlund and Martial. The other three positions we've got better depth than the vast majority of clubs yet we're still virtually out of options.