No, van Nistelrooy's was a surprise. We detected something off, sent him home and days later he broke down in training, as a PSV player. That's what you have medicals for.
It was the next year that we signed him after that known injury. See his own account
here
Byland, same thing. It was a big deal at the time, the Caf went into meltdown when he failed his medical, then lo and behold, spent his entire career ijured and retired in the Serbian League or something similarly obscure. Up there with Luiz Ronaldo in the "what may have been" stakes.