https://www.bbc.co.uk/news/health-52760871
Good development as the oxford vaccine is rolled out to trial in more than 10,200 people - including over 70s and five to 12-year-olds
Also interesting to read the paper on the monkeys which caused a bit of discussion, the full paper is worth a read
https://www.biorxiv.org/content/10.1101/2020.05.13.093195v1.full
These were the findings after euthanizing and autopsying the monkeys
Loads of other interesting and potentially promising things if translated to humans promising findings there. Usual caveats apply.
Good development as the oxford vaccine is rolled out to trial in more than 10,200 people - including over 70s and five to 12-year-olds
Also interesting to read the paper on the monkeys which caused a bit of discussion, the full paper is worth a read
https://www.biorxiv.org/content/10.1101/2020.05.13.093195v1.full
These were the findings after euthanizing and autopsying the monkeys
tl:dr, lungs in the vaccinated monkeys were normal and none of the pathological findings classic of severe covid disease found in themAt 7 days post inoculation, all animals were euthanized, and tissues were collected. None of the vaccinated monkeys developed pulmonary pathology after inoculation with SARS-CoV-2. All lungs were histologically normal and no evidence of viral pneumonia nor immune-enhanced inflammatory disease was observed. In addition, no SARS-CoV-2 antigen was detected by immunohistochemistry in the lungs of any of the vaccinated animals.
Two out of 3 control animals developed some degree of viral interstitial pneumonia. Lesions were widely separated and characterized by thickening of alveolar septae by small amounts of edema fluid and few macrophages and lymphocytes. Immunohistochemistry demonstrated viral antigen in type I and II pneumocytes, as well as in alveolar macrophages
Loads of other interesting and potentially promising things if translated to humans promising findings there. Usual caveats apply.