As a Pogba fan, I am also looking forward to seeing him back, but in my opinion his best position is not no. 10. His strengths are his (1) physical ability, allowing him to hold onto ball; (2) dribbling skills to bring the ball from back to front; (3) ridiculous passing range for quick transition. This skill set means he is more suitable for a deeper role responsible for organizing attack as well as antipressing, instead of a purely offensive duty.
On the other hand, he has certain weaknesses if he is played as a no. 10. His preference in dwelling onto ball sometimes delays attack and misses the best attacking opportunity. He is also not known for his pace, which may put him on a different wavelength against his teammates like James and Rashford. His inconsistency is another worry if we regard him as a no. 10.
Of course, Fred and McTominay's impressive performance in recent matches shouldn't be left unnoticed. It would be interesting to see how Ole arranges the gametime among them. In my opinion, we have already been lacking depth in midfield, it would be unwise to start all of them at the same time, especially with the upcoming congested fixtures.