Any word on who has traveled yet? I am pretty sure Romero and Shaw will start, Valencia probably rested as well. As for the rest, I really have no clue what kind of side José will go for. It's arguable that this is more important than the Sevilla game for a few reasons:
1) This is a one-off game against weaker opposition, we can get away with a draw/loss in Seville if we at least score and keep it tight.
2) We have a far better chance of winning the FA Cup than we do the Champion's League.
Despite this, there will definitely be changes such as I mentioned above. I'd hope some players can return, mainly Rashford and Herrera (I think Fellaini's injury is going to be the worst of the recent ones). If Pogba is really fully fit, then he needs to play here and play well to redeem himself before the Champion's League game. Make an impact.
Romero
Young Lindelof Rojo Shaw
McTominay Carrick Pogba
Mata Lukaku Sanchez
Despite people's reservations on certain players, I think the starting line-up against Sevilla will be something like this: de Gea; Valencia, Smalling, Jones, Young; Matic, Herrera, Pogba; Martial, Lukaku, Sanchez.