PL and CL: We should be aiming to compete for the title and get somewhere significant in the CL. I'd consider 2nd place in the league and a quarter final loss to someone better like Bayern, Madrid or Barca a successful season.
FA and League Cups: this season I'd rather see us prioritise giving youngsters genuine chances than trying to win at all costs. We have two big targets to focus on once again so neither success or failure in the domestic cups is going to seriously impact whether our season is seen as a successful one.
Therefore, allowing for loan spells obviously, Wilson, Januzaj, Pereira, McNair and Lingard should all be regulars in the side for both competitions. I'd also like to see game time for Pearson, Rothwell, Harrop and Varela (if he's still with us). Obviously the team for those kinds of games will constantly change, but an example side would look something like this:
2nd Keeper
Varela McNair Rojo Blind
Carrick Pearson
Pereira
Januzaj Wilson Lingard
Always take a strong bench, obviously: if at half time disaster looms, throwing on Rooney, Schweinsteiger and Herrera (for example) should be able to win you any game against lower-league opponents.