With Pogba, right at this moment:
Pogba Bruno
Fred
Without Pogba, right at this moment:
Bruno
McT Fred
Once McTominay has played himself back into full form and fitness, which we can expect to take a couple of weeks after such a long lay-off, I think he and Fred will be neck-and-neck for similar positions, prime for rotation.
Matic is a good option for the occasional game where we want to tighten up defensively... but actually not against top PL opposition, in my opinion, where his lack of pace or mobility makes him as much a liability as a strength. He's better used against tricky mid-table PL opposition or in big European games where his composure and experience come into play but where the pace of play isn't as relentless.