SARS CoV-2 coronavirus / Covid-19 (No tin foil hat silliness please)

noodlehair

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What's he on about in that briefing?

They only opened the pubs about 4 days ago, how can they possibly know that it hasn't had any effect on the infection rate?
 

africanspur

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I'm a doctor. I don't have cast iron job security, nor do a lot of other doctors, especially middle grade ones on training schemes with fixed end-date contracts. What its meant for locum GPs that I know is they've not been able to get jobs with telephone triages now taking up bulk of work in GP which the sessional GPs have been able to cover.

But I understand that there are people who are worse of. I don't think there's anybody who has said we want lockdown but we don't want financial protection for those hit hardest.
A little bit of it is self-preservation, I'm more likely to die from this disease if the hospital was overflowing with covid patients because of inadequate PPE which happened when we hit our peak. I don't want my patients to die either. I don't want my family member or friends who are clinically vulnerable to die either.
But I'm financially ok, I have a child so I'm well aware of educational issues. I'm also well aware and cognisant of safeguarding issues. And psychiatric and psychological impact that lockdown has on those socially shielding.

The fact is that a more widespread covid pandemic in my opinion would in the short and long term be worse for furloughing, worse for patients, worse for the economy, worse in every aspect. You won't need government to have a lockdown or legislate, not any would venture outside. That is not hyperbole. That is what would have happened without lockdown with rationing of ventilators, of oxygen. And this is still what can happen.

We should have locked down earlier and more severe measures before community spread got out of hand, during the delay phase doctors were literally begging CCGs, MPs to take what was happening in Italy more seriously. For mass testing etc. Groups like EveryDoctor, Doctor's Association UK, BMA have been behind a lot of what we've seen in our daily briefings. We then got told by government advisors that herd immunity was the strategy and behavioural science dictated lockdown would not be accept, more lobbying to MPs happened but it was too late by then.

There may be those for whom being able to work from home and being on 80% because of what they earn is ok for them. But I've not got to have that, I've been working in hell every day. And I'm cautious because frankly I know what this disease is and what it'll do if it goes unchecked.
I am also a doctor. Compared to almost every other job going, we do have cast iron job security. Short of gross negligence resulting in deaths or a consistent pattern of sexism/ racism etc, I struggle to see any real situation in which I (or most doctors) lose my/their job. This is not the case for almost any other job. If you're a consultant, a partner GP or salaried GP, you have to (generally) do something incredibly stupid or get incredibly unlucky (with a sprinkle of institutional racism) a la Bawa Garba to lose your job. Which means that for most doctors, once they've reached their mid 30s and reached what would generally be considered the end of their formal training as a GP or consultant, they pretty much have a job for life.

An F1 knows they will have a job for the next 2 years, cast-iron. If they're also not that bothered about speciality/ location, they will have a training job after that. I mean, some specialities in some areas are consistently under-filled. A 1st year trainee GP has a job guaranteed for the next 3 years. An IMT1 has a job for the next 3 years, an ST1 O&G/ Opthal trainee have one for the next 7 years I believe. An ST3 for the next 5 etc etc etc. Literally none of my juniors have had any difficulties getting jobs for this August, whether its for a training post, a fellow year or, for a lucky couple, with consultant jobs already laid out. The F2s have been a little more apprehensive about taking a year out to locum/ travel etc because of these circumstances.

Locum GPs and F3/F4s etc are a different matter because they have chosen a path, which I fully respect, which gives them infinitely more flexibility (and money!) than normal trainees. It is therefore not exactly strange that some of them are now scrambling a tad to get their normal shifts. If you pick something with more flexibility and money, its going to come with some negatives as well.

With all due respect, I'm not sure what the rest of the post has to do with what I actually posted. My post has nothing to do with being anti-lockdown, I am fully in favour of the lockdown and think we locked down too late and probably opened up too early as well (and what made it worse is that we started off between two different strategies and ended up doing neither one properly).

My point was in response to Wumminator, who (and I'm genuinely not trying to pile in here) was essentially suggesting that lockdown hasn't been that bad for kids/ teens. I was saying that the experience for middle and upper class families and kids has been utterly and wholly different from those of lower class kids and families. This isn't some fantasy I'm concocting, its fact. The former group are actually saving money at the moment, the latter taking out loans. The former are making sure their kids still continue to get as good an education as possible, the latter may be struggling to do so. According to the guardian article, up to 20% of the latter group have been receiving 0-1 hours of education a day for the past 4 months. 0-1 hours! That's insane.

So while I agree with the lockdown and think it has been and continues to be crucially important, I feel that many peoples' attitudes towards lockdown and its effects on certain groups within society has been quite flippant. Especially on this thread.

And it is very easy for us to say what's wrong with lockdown when we're either working in a hospital with our pretty reasonable salaries and not having to worry about having a job or working from home and on 100% salary with none of your normal expenses vs someone who....does not have these things.
 

Wumminator

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@africanspur - no need to worry about the pile on. I can absolutely see where people are coming from. I just think that some of the fears about the working class teenagers might be overblown. I think they’re a lot more resilient than we think and have a lot more issues than schools being shut for the lockdown period.
 

golden_blunder

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@africanspur - no need to worry about the pile on. I can absolutely see where people are coming from. I just think that some of the fears about the working class teenagers might be overblown. I think they’re a lot more resilient than we think and have a lot more issues than schools being shut for the lockdown period.
In Ireland 77% of our latest cases are under 25.
 

africanspur

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Was speaking to NHS nurses who had previously worked on a COVID ward today. One had suffered difficulty breathing, and the other had lost taste and smell. Both requested tests but were denied due to not having a temperature.

Both have done an antibody test in the months since and have the antibodies. I am still pretty annoyed, and I had this conversation hours ago
For a national system, I have to be honest, the variation between different areas has been shambolic imo. I have to be honest and say I feel a bit bad because, while we at one point had a huge number of patients with Covid, my trust was always in control and fully supportive of us. We were allowed to wear what PPE we felt safe in (within reason), certainly within certain departments. If you showed symptoms, you self isolated. We've been at the front of all the clinical trials and antibody testing has been rolled out to us too.

Contrast this to, for instance Ealing hospital (in Johnson's constituency) where a Healthcare assistant resigned early on because she kept on being told off for wearing a surgical mask while walking around (now compulsory in all hospitals) for not following PHE guidelines and for 'spreading panic'. This isn't the only such case either. It is just fecking infuriating.
 

africanspur

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@africanspur - no need to worry about the pile on. I can absolutely see where people are coming from. I just think that some of the fears about the working class teenagers might be overblown. I think they’re a lot more resilient than we think and have a lot more issues than schools being shut for the lockdown period.
Perfect, was just trying to explain the post, didn't want to make it seem like I was attacking again or anything. I know how difficult it can be if you're getting multiple replies at the same time. Though can also be very informative if people are polite and stay polite, which I'd like to think is what's happened here.

Personally, I wasn't even talking about just the psychological impact, though that obviously was a part of my post. And I'm sure some teens have seen it as all a bit of a laugh etc and are sitting at home playing fifa online with their friends. Guess I'm just worried about the difference in education they'll be receiving vs better off kids.
 

africanspur

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Is the border between Northern Ireland and the Republic still open as normal? Or was it closed like a lot of other EU borders?

Just had a look at your figures and you guys seem agonisingly close to 0 cases?
 

Pogue Mahone

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Is the border between Northern Ireland and the Republic still open as normal? Or was it closed like a lot of other EU borders?

Just had a look at your figures and you guys seem agonisingly close to 0 cases?
Been open the whole time. Closing that border is pretty much unthinkable.

We’ve been bumping along at between 10 and 20 cases for 2 or 3 weeks. One or two days we hit single digits. Realistically, we were still a good way off complete eradication when you consider very mild/asymptomatic cases. It was a good feeling having very low numbers though. Makes you feel very safe when you’re out and about. Which made a bit of a surge inevitable. People have got too comfortable.
 

africanspur

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Been open the whole time. Closing that border is pretty much unthinkable.

We’ve been bumping along at between 10 and 20 cases for 2 or 3 weeks. One or two days we hit single digits. Realistically, we were still a good way off complete eradication when you consider very mild/asymptomatic cases. It was a good feeling having very low numbers though. Makes you feel very safe when you’re out and about. Which made a bit of a surge inevitable. People have got too comfortable.
Must feel very nice! Think some of our shielding docs and nurses will start coming back in August apparently, I wouldn't feel particularly safe if I was them I must say. We're still in the hundreds of cases a day territory.
 

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I know some people here are fans of baldie, in my opinion, one of the best English language travel vloggers.
Very interesting story from him catching covid19 in Serbia. basically, young-ish man, thought he was covid19 invincible, took stupid risks, nearly dies.
Watch some of his previous video's and you'll visibly see just how much weaker he is now.

The number of people from abroad that I heard of catching it here is ridiculous.

Very interesting things happening here, in short:

- We had a hard lockdown in March and April and got through those months with very good results
- Elections have been scheduled for June the 20th and the government doctored the daily reports on infected/dead as they wanted the elections to go through. 50 people die in a day, they report 6, that kind of thing
- One week after the elections , they admit that the situation is getting out of control
- Three days ago, they announce another lockdown
- People respond to the lockdown announcement by staging massive protests that will inevitably cause the virus to spread even further. This is the third day of nation-wide protests
- After the first day of protests, the government have gone back on their lockdown decision
- Our hospitals will be completely overwhelmed at some point next week

Takeaways:
- God help us all
- If I suddenly stop posting I would like to say that this forum has been a huge part of my life, as I read much more than I post, and would like to thank you all for all the fun and great discussions over the years.
 

Hound Dog

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Are you in a risk group or 70+?
I am 32 with no underlying conditions.

I am aware that I will likely be fine if I get it. I am just a bit depressed to see our government do this to us. I never thought much of them but this is a new low.

They are also reporting a surprisingly high number of young people on ventilators so I am no longer sure what is happening and whether it is as relatively harmless to us as it used to be/was thought to be
 
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I am 32 with no underlying conditions.

I am aware that I will likely be fine if I get it. I am just a bit depressed to see our government do this to us. I never thought much of them but this is a new low.

They are also reporting a surprisingly high number of young people on ventilators so I am no longer sure what is happening and whether it is as relatively harmless to us as it used to be/was thought to be
It's an awful situation for all governments in fairness, the next year is gonna be extremely difficult for everyone to find a balance.

Just be sensible with your social distancing, all the stats show that the average age on ICU is 60+ and average age of death higher still, and then still, the majority being admitted to ICU have underlying conditions, nothing has changed there.
 

Wibble

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Just on the herd immunity thing, I’ve heard a few virologists say that eradication is off the table for any virus that has human and animal hosts. No matter how high you get immunity in people, the virus can hang out amongst animals before making a comeback when human immunity declines. Then we have the idiots who refuse to get vaccinated, which seems to be a bigger problem now than ever before in the history of vaccines.

I’m getting more and more certain this virus will never go away. The best possible outcome for me is we get a decent vaccine (although I think this will most likely be waiting at least another couple of years before it’s rolled out) to protect the most vulnerable and the virus becomes less virulent (this is more in hope than expectation, as it seems to be fairly stable) Otherwise it’s just a case of learning to live with it for the forseeable future. Which sucks but there you go. I definitely think outbreaks will get easier and easier to manage, as more and more people get infected. So that’s another positive, I guess.
I was talking about eradication at a local level and worldwide eradication prior to a vaccine is functionally impossible. We perhaps all had a small window of opportunity early on in the pandemic but now we need to minimise deaths and the huge ongoing, often permanent, harm to many who don't die until vaccines are developed (and there will be quite a few vaccines).

That said eradication of a virus that originated in animals is possible e.g. smallpox. Of course it isn't a given as we don't currently know how the virus passed from the last animal host to humans and therefore how likely another animal-hunan transmission is and we don't know how universal vaccination against SARS-CoV-2 will becorchow long immunity will last etc etc.

So I too doubt that tital.eradication will ocvur but thatvit will hopefully become onevof those nasty but rare viral infections thayvmostbof us don't need to worry thst much about (in this case due to universal vaccination. Until then we need to minimise thechatm to people.
 

Wibble

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Just on the herd immunity thing, I’ve heard a few virologists say that eradication is off the table for any virus that has human and animal hosts. No matter how high you get immunity in people, the virus can hang out amongst animals before making a comeback when human immunity declines. Then we have the idiots who refuse to get vaccinated, which seems to be a bigger problem now than ever before in the history of vaccines.

I’m getting more and more certain this virus will never go away. The best possible outcome for me is we get a decent vaccine (although I think this will most likely be waiting at least another couple of years before it’s rolled out) to protect the most vulnerable and the virus becomes less virulent (this is more in hope than expectation, as it seems to be fairly stable) Otherwise it’s just a case of learning to live with it for the forseeable future. Which sucks but there you go. I definitely think outbreaks will get easier and easier to manage, as more and more people get infected. So that’s another positive, I guess.
I was talking about eradication at a local level and worldwide eradication prior to a vaccine is functionally impossible. We perhaps all had a small window of opportunity early on in the pandemic but now we need to minimise deaths and the huge ongoing, often permanent, harm to many who don't die until vaccines are developed (and there will be quite a few developed).

That said eradication of a virus that originated in animals is possible e.g. smallpox. Of course it isn't a given as we don't currently know how the virus passed from the last animal host to humans and therefore how likely another animal-hunan transmission is and we don't know how universal vaccination against SARS-CoV-2 will be or how long immunity will last etc etc.

So I too doubt that total.eradication will occur but hope that it will become one of those nasty but rare viral infections that most of us don't need to worry that much about (in this case due to almost universal vaccination). Until then we need to minimise the harm to people.
 

One Night Only

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Covid19 knock on effects into UK unemployment really starting to kick in, It's going to be a jobs massacre.

They were planning this last year. It's not due to covid 19, it's to do with their shit business model and overpriced crap.

Where has that video even came from? Looks like something a Facebook warrior has made, shit music, no actual information, and just writing, no speaking. Always a sign of absolute crap tbh.
 

Wibble

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With respect Wibble, discussing this particular topic with you is a bit like discussing Brexit with Paul. We are agreed on almost everything but some positions taken are so extreme (in my own view of course) that it is difficult to reconcile.
You need to avoid the noise around the fundamentals of things and you can't get past the fact that severely reducing the R and keep it down. Many measures help e.g. social distancing and mask wearing (in some circumstances) etc. Locking down of countries, regions, suburbs and even buildings can be a response to deal with outbreaks but it is just as important in a more strategic way. Each restricted region is a cell and if you can eradicate the virus (or at least get it to a very very low rate of community transmission) from that cell you need little or no effort to keep it that way. Once there are many cells you can open them up to each other without risking the other open cells. Maybe you then get to some countries being functionally covid free which can then join up e.g. NZ and AU if we can get Victoria under control and we haven't fecked up by opening the borders too early (IMO we did by a few weeks). In the UK's case the lock down of the population was largely wasted effort because the clowns in charge freely allowing the import of covid from everywhere without even basic testing, much less a quarantine.

44,000 deaths in the UK vs 106 in Australia which has a population about 40% the size of the UK's. And excess deaths are likely to be at least 60,000.

Loosing sight of the fundamentals of all this is why so many places are in such a terrible state and will be again when second waves strike in colder weather as seems likely.

The 'evidence' that we will get a vaccine that actually works well, is not particularly of that much interest to me until it can show a genuine positive impact in phase 3 and 4 trials.

I'm also quite concerned that we'll end up rushing through vaccines that don't work properly to get a 'win', in the same way we pushed tamiflu in the last pandemic or are pushing remdesevir now.
It should be because ultimately this is the only way out of this shit show. The chances of us not having a viable vaccine soon is now looking close to zero. So many are in production that even if some prove ineffective and others have side-effect serious enough to stop progress (quite rare with modern vaccines, as opposed to drugs) we will still almost certainly have enough options to makes this "just another (far more harmful) flu" in years to come.

My main issue is that you have also said that Europe for instance should take an approach similar to NZ and Australia. This is of course totally impossible, in a landmass which is only about 1/3 bigger than Australia's but with approximately 20 times the population (or 40 times NZ's landmass, with 100 times their population) and infinitely more inter-connected with each other than those countries could ever be.
It was possible but the will wasn't there. Maggie (much though I despise her) would have had the UK locked down tighter than a ducks arse and feck what anyone said or thought. Boris tied to pretend it wasn't there, nearly killed himself in the process and now just bumbles around uselessly. Countries need strong and authentic leadership at times like this and it is lacking almost everywhere. Here in Australia only some State premiers refusing to open up when told/asked to by our idiot in chief saved us all from suffering Victoria's fate (and even that may be savable even with 1-200 infections per day).

The NZ PM, as great as she is, and as amazing a job as she has done so far, doesn't know what the long term economic impacts of the various different approaches taken and the reality is, as much as we can model and estimate, nobody anywhere knows with any certainty what they will be.

Hence my own issue when people talk in such absolutes in a situation which is still very novel to us.
She took the only sensible step, as did Australia to a lesser degree. Unnecessary deaths are unacceptable and the early economic hit is justified especially as it allows you not to stop normal medical procedures and keep everyday life going and largely back to normal. The economic benefit later will be significant. The only way this doesn't work is if we never get a vaccine, which is unlikely, but even if that does happen it was still the right decision as morality should trump economics. That should be an absolute.
 

Wibble

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What's he on about in that briefing?

They only opened the pubs about 4 days ago, how can they possibly know that it hasn't had any effect on the infection rate?
Dominic Cummings went for a drive and didn't spot anything so all must be ok.
 

Wibble

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Victoria (well Melbourne) is close to being out of control. 288 new infections today and the majority community transmission of unknown source. 8 of the 9 locked down towers were caught early enough to prevent mass transmission and have been returned to normal (normal now being stage 3 lockdown) with 1 having the full lock-down extended to allow for full testing and possibly medical evacuation of anyone infected (still to be decided). All caused by a single breakdown in infection protocols at a quarantine hospital combined with poor social distancing and not complying with group meeting size regulations, then compounded by a cold snap in winter. It shows how infectious this is especially in winter conditions.

So far it hasn't been exported to other states but watch this space. It could have got out ahead of the border being shut again.
 

africanspur

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You need to avoid the noise around the fundamentals of things and you can't get past the fact that severely reducing the R and keep it down. Many measures help e.g. social distancing and mask wearing (in some circumstances) etc. Locking down of countries, regions, suburbs and even buildings can be a response to deal with outbreaks but it is just as important in a more strategic way. Each restricted region is a cell and if you can eradicate the virus (or at least get it to a very very low rate of community transmission) from that cell you need little or no effort to keep it that way. Once there are many cells you can open them up to each other without risking the other open cells. Maybe you then get to some countries being functionally covid free which can then join up e.g. NZ and AU if we can get Victoria under control and we haven't fecked up by opening the borders too early (IMO we did by a few weeks). In the UK's case the lock down of the population was largely wasted effort because the clowns in charge freely allowing the import of covid from everywhere without even basic testing, much less a quarantine.

44,000 deaths in the UK vs 106 in Australia which has a population about 40% the size of the UK's. And excess deaths are likely to be at least 60,000.

Loosing sight of the fundamentals of all this is why so many places are in such a terrible state and will be again when second waves strike in colder weather as seems likely.

It should be because ultimately this is the only way out of this shit show. The chances of us not having a viable vaccine soon is now looking close to zero. So many are in production that even if some prove ineffective and others have side-effect serious enough to stop progress (quite rare with modern vaccines, as opposed to drugs) we will still almost certainly have enough options to makes this "just another (far more harmful) flu" in years to come.

It was possible but the will wasn't there. Maggie (much though I despise her) would have had the UK locked down tighter than a ducks arse and feck what anyone said or thought. Boris tied to pretend it wasn't there, nearly killed himself in the process and now just bumbles around uselessly. Countries need strong and authentic leadership at times like this and it is lacking almost everywhere. Here in Australia only some State premiers refusing to open up when told/asked to by our idiot in chief saved us all from suffering Victoria's fate (and even that may be savable even with 1-200 infections per day).

She took the only sensible step, as did Australia to a lesser degree. Unnecessary deaths are unacceptable and the early economic hit is justified especially as it allows you not to stop normal medical procedures and keep everyday life going and largely back to normal. The economic benefit later will be significant. The only way this doesn't work is if we never get a vaccine, which is unlikely, but even if that does happen it was still the right decision as morality should trump economics. That should be an absolute.
Again, I respectfully refer you to my initial line regarding my feelings on the futility of this particular conversation and will pretty much leave it there. I've said multiple times that I do not understand how people are so insistent on using absolutes for a situation that has little precedent.

The only thing I will point out is that it is not that I am uninterested in the vaccine trials. It is that many simultaneously happening does not mean that we will definitely get a vaccine. I am not interested if there are 2 trials or 200 trials frankly, what I'm interested in is the actual data on efficacy etc once it comes out. And as I've said, I am incredibly worried that we will rush through a vaccine because we need a 'win', only to discover a few years later that it doesn't provide very good immunity or causes certain horrible SE, causing unbelievable damage in humanity's fight against the ridiculous anti-vaxxers.
 

Pogue Mahone

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Again, I respectfully refer you to my initial line regarding my feelings on the futility of this particular conversation and will pretty much leave it there. I've said multiple times that I do not understand how people are so insistent on using absolutes for a situation that has little precedent.

The only thing I will point out is that it is not that I am uninterested in the vaccine trials. It is that many simultaneously happening does not mean that we will definitely get a vaccine. I am not interested if there are 2 trials or 200 trials frankly, what I'm interested in is the actual data on efficacy etc once it comes out. And as I've said, I am incredibly worried that we will rush through a vaccine because we need a 'win', only to discover a few years later that it doesn't provide very good immunity or causes certain horrible SE, causing unbelievable damage in humanity's fight against the ridiculous anti-vaxxers.
I actually think that’s quite likely. Everyone I’ve heard/read who is an expert on Coronaviruses seems to think making a very effective, long-lasting virus is extremely difficult. All you need to do is look at what happens when you stimulate your immune system naturally.

If you catch measles or chickenpox you’ll almost certainly never catch it again. Hence we have effective vaccines that give permanent immunity. If you get infected with the common cold Coronavirus then you can catch it again a year later. Why would artificially stimulating your immune system with the same antigen have a different outcome?

Thankfully, I think we can get by with a “good enough” vaccine. One that reduces severity and/or needs regular boosters but won’t give complete protection to everyone who gets it. It won’t eradicate the virus (something anti-vaxxers will also sabotage) but it will make it easier to live with. Which is, I think, the best we can hope for. I also think we’ll end up with different vaccines used in different parts of the world. The idea of a single “magic bullet” that gives the whole world immunity is a pipe dream.
 

JPRouve

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I actually think that’s quite likely. Everyone I’ve heard/read who is an expert on Coronaviruses seems to think making a very effective, long-lasting virus is extremely difficult. All you need to do is look at what happens when you stimulate your immune system naturally.

If you catch measles or chickenpox you’ll almost certainly never catch it again. Hence we have effective vaccines that give permanent immunity. If you get infected with the common cold Coronavirus then you can catch it again a year later. Why would artificially stimulating your immune system with the same antigen have a different outcome?

Thankfully, I think we can get by with a “good enough” vaccine. One that reduces severity and/or needs regular boosters but won’t give complete protection to everyone who gets it. It won’t eradicate the virus (something anti-vaxxers will also sabotage) but it will make it easier to live with. Which is, I think, the best we can hope for. I also think we’ll end up with different vaccines used in different parts of the world. The idea of a single “magic bullet” that gives the whole world immunity is a pipe dream.
Are they like the ones I have heard/read? Basically they don't know, they are the only ones without certitudes which is why I've been skeptical about all these announcements about vaccines or how the virus may or may not evolve. Listening to coronavirus experts, the only thing they know is that it's one of the most adaptable virus family.
 

sun_tzu

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Thankfully, I think we can get by with a “good enough” vaccine. One that reduces severity and/or needs regular boosters but won’t give complete protection to everyone who gets it. It won’t eradicate the virus (something anti-vaxxers will also sabotage) but it will make it easier to live with. Which is, I think, the best we can hope for. I also think we’ll end up with different vaccines used in different parts of the world. The idea of a single “magic bullet” that gives the whole world immunity is a pipe dream.
that seems a realistic possibility - though I do wonder if ultimately we miht get some if not total heard immunity before that happens given the fact that the timescales are likley to be years not months and how rapidly the virus has spread to date
 
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that seems a realistic possibility - though I do wonder if ultimately we miht get some if not total heard immunity before that happens given the fact that the timescales are likley to be years not months and how rapidly the virus has spread to date
Herd immunity can start having a huge effect even at 30%, which is often not mentioned when people bring up this subject.
 

Pogue Mahone

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that seems a realistic possibility - though I do wonder if ultimately we miht get some if not total heard immunity before that happens given the fact that the timescales are likley to be years not months and how rapidly the virus has spread to date
Kind of. You can catch the common cold coronavirus more than once. So they did a study where they dosed volunteers with the virus twice, 12 months apart. Almost all of them became reinfected but most of them had much less symptoms after the second dose. I think the most likely scenario - while waiting for a vaccine - is seasonal epidemics, with less of a burden on the health service each year, thanks to more and more people having either partial immunity or only very mild illness.
 

sun_tzu

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Herd immunity can start having a huge effect even at 30%, which is often not mentioned when people bring up this subject.
I didnt know it was that low - thought it was more like 50% with 75% giving very strong protection but yeah anything has to help and of course it remains to be seen if the virus mutates but if it does not then you would think that in a year or so some heard immunity protection (and better antiviral treatments / better experience) is our best bet in the very short term for at least some improvements.
Even if a vaccine is found I suspect it must be a huge logistical challenge to scale up production and delivery / application - even without the potential commercial wranglings and countries competing against each other - and with that factored in it seems even more difficult to see an effective vaccine delivered to enough people round the world in a short timespan
 

sun_tzu

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Kind of. You can catch the common cold coronavirus more than once. So they did a study where they dosed volunteers with the virus twice, 12 months apart. Almost all of them became reinfected but most of them had much less symptoms after the second dose. I think the most likely scenario - while waiting for a vaccine - is seasonal epidemics, with less of a burden on the health service each year, thanks to more and more people having either partial immunity or only very mild illness.
given where we were a few weeks ago that seems more manageable than total indefinite lockdowns or finding a magic bullet type cure
 

Port Vale Devil

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Again, I respectfully refer you to my initial line regarding my feelings on the futility of this particular conversation and will pretty much leave it there. I've said multiple times that I do not understand how people are so insistent on using absolutes for a situation that has little precedent.

The only thing I will point out is that it is not that I am uninterested in the vaccine trials. It is that many simultaneously happening does not mean that we will definitely get a vaccine. I am not interested if there are 2 trials or 200 trials frankly, what I'm interested in is the actual data on efficacy etc once it comes out. And as I've said, I am incredibly worried that we will rush through a vaccine because we need a 'win', only to discover a few years later that it doesn't provide very good immunity or causes certain horrible SE, causing unbelievable damage in humanity's fight against the ridiculous anti-vaxxers.

Good video from the BBC explaining a little bit about immunity

https://www.bbc.co.uk/news/av/53319735/can-you-get-coronavirus-twice
 

JPRouve

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I didnt know it was that low - thought it was more like 50% with 75% giving very strong protection but yeah anything has to help and of course it remains to be seen if the virus mutates but if it does not then you would think that in a year or so some heard immunity protection (and better antiviral treatments / better experience) is our best bet in the very short term for at least some improvements.
Even if a vaccine is found I suspect it must be a huge logistical challenge to scale up production and delivery / application - even without the potential commercial wranglings and countries competing against each other - and with that factored in it seems even more difficult to see an effective vaccine delivered to enough people round the world in a short timespan
It depends on how infections a virus is which is why that low figure is irrelevant in this case.
 

Stack

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Herd immunity can start having a huge effect even at 30%, which is often not mentioned when people bring up this subject.
I was of the understanding that herd immunity is different for different diseases because of the infection rates etc. Also was of the understanding that herd immunity for coronavirus was up around 60% approximately. Hadnt heard it was as low as 30%.
 

sun_tzu

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It depends on how infections a virus is which is why that low figure is irrelevant in this case.
I was of the understanding that herd immunity is different for different diseases because of the infection rates etc. Also was of the understanding that herd immunity for coronavirus was up around 60% approximately. Hadnt heard it was as low as 30%.
Thanks...

and on a more depressing note I see the trend line for deaths in the USA has gone up (mirroring the reported cases number with approx a 2 week lag) ... as the reported cases has been increasing for that 2 weeks it looks like the USA is about to either have to lock down again quickly or things are gonna get out of control ( I suspect the latter)
 

JPRouve

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I was of the understanding that herd immunity is different for different diseases because of the infection rates etc. Also was of the understanding that herd immunity for coronavirus was up around 60% approximately. Hadnt heard it was as low as 30%.
It is. And Regulus is also probably mixing immunity rate and herd immunity, the first one is just the proportion of people that have an immunity and whatever the figure it will always have an effect on how the virus will spread, the higher the figure the more difficult it is for large community spread. Herd immunity is the point where the immunity rate is high enough that the virus has next to no chance to spread widely because the herd as whole is seroprotected. Some viruses require a vaccination rates in the 40s-50s while others are in the 90s.
 

Pogue Mahone

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It is. And Regulus is also probably mixing immunity rate and herd immunity, the first one is just the proportion of people that have an immunity and whatever the figure it will always have an effect on how the virus will spread, the higher the figure the more difficult it is for large community spread. Herd immunity is the point where the immunity rate is high enough that the virus has next to no chance to spread widely because the herd as whole is seroprotected. Some viruses require a vaccination rates in the 40s-50s while others are in the 90s.
Which always makes me think how insanely contagious measles is. Infection or vaccine gives complete life long immunity and there are no animal hosts, yet we still can’t maintain herd immunity after vaccination programs lasting decades.