It wont be a good look for ETH if he ditches Antony -- that means he doesn't start the majority of his Eredivisie Specials and most of his transfers other than Onana.
Martinez will start when fit.
Malacia was a cheap backup, Eriksen (if we're counting him as a former Ajax player) was a free option and plays frequently (too frequently, tbh).
Hojlund, Casemiro likely starters. Amrabat a regular if not first XI but price reflects that.
Mount and Antony so far are the two big money transfers who don't look they should be playing and potentially big mistakes. It's not great but it's only two of his signings (albeit two of the three most expensive, and the other in Hojlund isn't producing yet but perhaps his age and the lack of service affords him some grace).
Regardless of how it looks dropping him though, it looks worse persisting with him. If Amad was fit it'd at least be an option take Antony out of the spotlight a bit, and he could be the one making late 15-20 minute appearances against tired defences which might help his confidence level.