SARS CoV-2 coronavirus / Covid-19 (No tin foil hat silliness please)

LordNinio

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hobbers

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https://www.dw.com/en/coronavirus-the-tide-is-coming-for-medicinal-cannabis/a-53371342

Study in Canada (Lethbridge University) suggests that cannabis can prevent the virus from binding onto you. (similar to that nicotine study posted here several days ago)
ACE2 is also a pretty likely explanation as to why the virus is more dangerous to men (men have more ACE2 receptors than women), and also why there have been many cases of people who seem to eventually fight off the pneumonia-like symptoms only to be then tragically struck down by a heart infection (ACE2 is also found in heart tissue). Might also be a factor in the disparities between different ethnicities.
 

redshaw

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If you're interested in information on reopening office workplaces safely, there are good guides at http://www.cibse.org/coronavirus-covid-19/emerging-from-lockdown

Surfaces and close contact are still greater risks than aerosols, but definitely appears to be important to ensure good ventilation.
Surfaces probably not but of course people should still be careful. A German study couldn't find a living virus in 70 live infected households, just dead traces. It doesn't survive outside of a droplet and they will dry up fast on surfaces and dissolve on skin and clothes. It's probably close contact inhalation and sustained inhalation of smaller droplets in confined environments from work/tube trains/indoor events/dining/drinking to home which is all tied together. I'm posting about all these environments, not just offices.

Link again for anyone else.
https://www.erinbromage.com/post/the-risks-know-them-avoid-them
 
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Suedesi

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I’ve been thinking about this a bit recently. What are the long term prospects for countries like NZ and Aus that stop spread completely? If they effectively banish the virus from their countries that’s great news in the short term but if a vaccine takes several years (which is a definite possibility) then countries that have had a constant trickle of cases will likely be able to get back to a relatively normal way of life while “virus free” countries are completely shut off from the rest of the world, under the constant threat of another lockdown.

If it turns out that a safe/effective vaccine is NEVER going to happen (which is also possible) then they’re absolutely fecked. What would their strategy be then?
Surely NZ/AUS can screen any passenger that comes into their country? If you come in through airports you can submit to a test at your country of origin and by the time you land (assuming it's a long ass flight) your results should be ready. If negative, you're allowed in, if not the whole plane gets quarantined and dealt with.

It's expensive and cumbersome, but it can be done - not to mention cheaper than the alternative (which would presumably be quarantining the whole country again).
 

RK

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Surfaces probably not but of course people should still be careful. A German study couldn't find a living virus in 70 live infected households, just dead traces. It doesn't survive outside of a droplet and they will dry up fast on surfaces and dissolve on skin and clothes. It's probably close contact inhalation and sustained inhalation of smaller droplets in confined environments from work/tube trains/indoor events/dining/drinking to home which is all tied together. I'm posting about all these environments, not just offices.

Link again for anyone else.
https://www.erinbromage.com/post/the-risks-know-them-avoid-them
That was a good read, thanks. Especially the case studies.
 

0le

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https://www.erinbromage.com/post/the-risks-know-them-avoid-them

Good article that sums up some of the bits I've posted on here in the past 2 months like the Chinese restaurant, LA choir and ventilation being key indoors and adds some other examples like a call centre and indoor sporting event

This is potentially key information for places of work opening up soon and not walking into a huge second wave. Washing hands, cleaning your phone and keeping 1-2 metres apart won't help indoors and most is spread at home.
I had a look at that article. First of a lot is not referenced.

A Cough: A single cough releases about 3,000 droplets and droplets travels at 50 miles per hour. Most droplets are large, and fall quickly (gravity), but many do stay in the air and can travel across a room in a few seconds.

A breath: A single breath releases 50 - 5000 droplets. Most of these droplets are low velocity and fall to the ground quickly. There are even fewer droplets released through nose-breathing. Importantly, due to the lack of exhalation force with a breath, viral particles from the lower respiratory areas are not expelled.
How far a droplet travels really depends on quite a few factors. Saying most droplets are "large" doesn't mean anything in this context. Saying droplets fall quickly due to gravity alone is only half the picture. Some of the droplets will also settle faster because of the additional momentum (and consequently a velocity component) they gained during the sneeze/cough etc. Think of it like firing a gun downwards - the bullet will fall because of gravity and also the energy imparted onto the bullet by the mechanism in the gun. Compare that to just dropping a single bullet from your hand from a great height and watching it fall due to gravity.

But even if that cough or sneeze was not directed at you, some infected droplets--the smallest of small--can hang in the air for a few minutes, filling every corner of a modest sized room with infectious viral particles. All you have to do is enter that room within a few minutes of the cough/sneeze and take a few breaths and you have potentially received enough virus to establish an infection.
If there is a negligible amount of motion in the air, it is very unlikely the smallest droplets will fill quickly every corner of a modest sized room. Molecular transport processes take a long time to transport contaminants across large distances. This is discussed in the seminal book by Lumley in Chapter 1 in "A first course turbulence", see page 8-9 [here]. If there is a small degree of motion, then it is possible. But you need to also then consider that greater motion may also lead to greater evaporation.

Small sized droplets (less than 5 micron) can be considered those which follow the air flow well but they can also evaporate very quickly, see for example [here]. Small droplets in this context can also be called "tracers", again, the meaning is that they "trace" or follow the air flow (its instantaneous streamlines) very well. Droplets greater than this size may not follow the air very well. So if a group of air molecules goes in one direction, the "larger" droplet in that same region may not go in the same direction.

The important point from the paper is:

very high gas flow rates can .... increase droplet evaporation.

Water fast evaporation can be a serious problem when long droplet lifetimes are needed. It is for this reason that it is seldom used as fluid for tracer droplets.

after a short time and depending on the carrying gas humidity, most of the water will have evaporated,
They measured the velocity of air, using these "tracer" droplets when the air flow was 10m/s. So effectively the droplets were moving at 10m/s and evaporation was an issue. 10m/s is about 22mph. So you can imagine how problematic evaporation could be at 200mph, as is the claimed velocity of the droplets during a sneeze. Evaporation is not my background, but it is definitely something which is being ignored by articles that I am reading. I would like to see an article which explains this process specifically, rather than articles trying to explain dispersion properties which are based on obscure simulations or very niche experiments.

By the way, how far two droplets separate is a topic called "pair dispersion", more specifically inertial pair dispersion and the wealth of papers in this topic may also give some insight regarding how a cloud of droplets disperses (and separates).
 
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0le

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That was a good read, thanks. Especially the case studies.
If you want insight, read review papers from annual review journal publications e.g. [here], textbooks e.g. [here], or listen to qualified individuals giving lectures (on Youtube for example). You shouldn't read random articles which do not do a good job of explaining anything at all and worse still add very few references. Whilst the article is written by a person within biology, people who specialise in biology are probably not qualified to speak about droplet dispersion in quiescent and turbulent flows.
 
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sammsky1

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If you want insight, read review papers from annual review journal publications e.g. [here], textbooks e.g. [here], or listen to qualified individuals giving lectures (on Youtube for example). You shouldn't read random articles which do not do a good job of explaining anything at all and worse still add very few references. Whilst the article is written by a person within biology, people who specialise in biology are probably not qualified to speak about droplet dispersion in quiescent and turbulent flows.
Genuine question: what is your level of expertise is on this subject?

PS: the author makes his position clear on his blog, citing qualifications and caution on what he has written. I thought it was excellent

https://www.erinbromage.com/post/about-the-author-professor-erin-bromage
 
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0le

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Genuine question: what is your level of expertise is on this subject?

PS: the author makes his position clear on his blog, citing qualifications and caution on what he has written. I thought it was excellent

https://www.erinbromage.com/post/about-the-author-professor-erin-bromage
I have a PhD in experimental multiphase flows, specifically droplet and particle dispersion in turbulent flows and the study of droplet-droplet/particle collisions. That doesn't really imply I understand anything (I really don't understand much at all). However, I do have some awareness of the important topics by exposure of reading hundreds of literature papers (at least 50 in full), vast amounts of sections/chapters in textbooks and carrying out experiments using well established laser diagnostic techniques in the field, which also required using a half face reusable face mask. The latter is why I felt I could give my opinion about them earlier in the thread - I spent a good amount of time using one. I also used reusable FFP2 masks.
 
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The Purley King

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.......,Basically, I worry that countries with closed borders and single digit prevalence will have a much higher chance of needing to go into lockdown again in the future than those who’ve been a little less successful at flattening the curve this time round.
I think you are right. If we don’t get a vaccine for a couple of years, or ever, which seems entirely possible then having no natural immunity in the population surely makes that country much more vulnerable to future outbreaks.
New Zealand might be playing a much longer game than anyone else.
Whether that is preferable or not I’m not sure.
 

jojojo

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I have to be extremely careful and keep a distance , mother in law is brilliant , she has got it but through no fault of his own my father in law constantly forgets so you have to be on the ball. Loneliness is a terrible thing too and I dread to think how he would be if anything happened to her , he totally relies on her and she needs some help.
You're doing something important. Your visit is probably as close to a few minutes of respite support as she gets at the moment. Just having someone to share part of the day, and break what can be a stifling pattern for a little while, is a huge thing, even if your do have to maintain a distance.

In terms of the government guidance:
"any medical need, including to donate blood, avoid injury or illness, escape risk of harm, or to provide care or to help a vulnerable person." That's a broad and (deliberately) open definition, and it is what you're doing.
 

RoadTrip

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I have a PhD in experimental multiphase flows, specifically droplet and particle dispersion in turbulent flows and the study of droplet-droplet/particle collisions. That doesn't really imply I understand anything (I really don't understand much at all). However, I do have some awareness of the important topics by exposure of reading hundreds of literature papers (at least 50 in full), vast amounts of sections/chapters in textbooks and carrying out experiments using well established laser diagnostic techniques in the field, which also required using a half face reusable face mask. The latter is why I felt I could give my opinion about them earlier in the thread - I spent a good amount of time using one. I also used reusable FFP2 masks.
Completely take your point and everything you’ve written makes sense for sure. And agree that the article in question didn’t contain proper references etc.

Having said that, in trying to simplify the topic, am I right in saying the theme of that article is correct? Ignoring the specific assertions within it to speed and extent of disputation, I think the main point of the article being to demonstrate what factors increase virus spread at a high level remain relatively salient?
 

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South Korea says there are now 101 new cases of coronavirus linked to a nightclub district in Seoul

On the BBC. This is unsurprising, as nightclubs serve pretty much the opposite purpose to social distancing
 

lynchie

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Surfaces probably not but of course people should still be careful. A German study couldn't find a living virus in 70 live infected households, just dead traces. It doesn't survive outside of a droplet and they will dry up fast on surfaces and dissolve on skin and clothes. It's probably close contact inhalation and sustained inhalation of smaller droplets in confined environments from work/tube trains/indoor events/dining/drinking to home which is all tied together. I'm posting about all these environments, not just offices.

Link again for anyone else.
https://www.erinbromage.com/post/the-risks-know-them-avoid-them
I disagree. This study found the virus was stable on surfaces for much longer than in air. This is why cleaning of high contact surfaces is so important, as well as good ventilation.

https://www.nejm.org/doi/full/10.1056/NEJMc2004973
 

TheGame

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I have been visiting my mother and father in law near enough daily , they are in their 80s and he has alzheimers , it is incredibly difficult for my mother in law . Thankfully the weather has been good and we have sat outside in the garden a good 4 metres apart . I take a flask so when I have a cuppa they dont have contact , they make their own and mine goes home with me. I spray my chair down with disinfectant when I leave and they never touch it anyway . Without my visits my mother in law would struggle in isolation with a man that she has to remind every ten mins that they can`t go out because of the virus and no one normal to talk to.
I agree with you mate, mental health is a massive issue. I don't see an issue with what you are doing, I was just pointing out the advice. It's hard for the older people and especially if they have other conditions and the toll this is taking on everyone's mental health has been understated.
 

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Surely NZ/AUS can screen any passenger that comes into their country? If you come in through airports you can submit to a test at your country of origin and by the time you land (assuming it's a long ass flight) your results should be ready. If negative, you're allowed in, if not the whole plane gets quarantined and dealt with.

It's expensive and cumbersome, but it can be done - not to mention cheaper than the alternative (which would presumably be quarantining the whole country again).
That isn’t watertight, which is why most countries are enforcing 14 day quarantines. Someone who has only just been exposed to the virus might not test positive until a few days after getting infected
 

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I've not verified if that's true or not but if so then we continue to show ourselves incapable. Looking at the response of some unions it seems likely to be true.

One of the ideas of the lockdown was to prepare for the next wave. Are you telling me they couldn't have announced guidelines for safe working during the next phase before or at worse in line with the Boris announcement? Employers and employees should have specific guidance to work from.
 

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I have a PhD in experimental multiphase flows, specifically droplet and particle dispersion in turbulent flows and the study of droplet-droplet/particle collisions. That doesn't really imply I understand anything (I really don't understand much at all). However, I do have some awareness of the important topics by exposure of reading hundreds of literature papers (at least 50 in full), vast amounts of sections/chapters in textbooks and carrying out experiments using well established laser diagnostic techniques in the field, which also required using a half face reusable face mask. The latter is why I felt I could give my opinion about them earlier in the thread - I spent a good amount of time using one. I also used reusable FFP2 masks.
Talk about ITK!

So lucky how many actual smart people we have on this forum.
 

Pogue Mahone

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If you want insight, read review papers from annual review journal publications e.g. [here], textbooks e.g. [here], or listen to qualified individuals giving lectures (on Youtube for example). You shouldn't read random articles which do not do a good job of explaining anything at all and worse still add very few references. Whilst the article is written by a person within biology, people who specialise in biology are probably not qualified to speak about droplet dispersion in quiescent and turbulent flows.
I thought they did a pretty good job of explaining and - while it wasn’t comprehensive enough to be peer reviewed - they did provide references. Was there any element of it you particularly disagreed with? I know a bit about biology but feck all about droplet dispersion.
 

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I've not verified if that's true or not but if so then we continue to show ourselves incapable. Looking at the response of some unions it seems likely to be true.

One of the ideas of the lockdown was to prepare for the next wave. Are you telling me they couldn't have announced guidelines for safe working during the next phase before or at worse in line with the Boris announcement? Employers and employees should have specific guidance to work from.
Workplaces get hours to implement Covid-secure environments, Gov get 4 weeks to implement testing rises, airport quarantines and so on. It's a farce.
 

Smores

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Hancock needs a holiday, that man is done. I'm finding their messaging on 'face coverings' annoying, they're so desperate not to be seen to do a u-turn they're advising they should be worn whilst at the same time saying we didn't do it earlier because there's no evidence.

People aren't going to wear them when they hear such messages. Be a grown up and explain why they're now needed and why the message has changed.
 

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Hancock needs a holiday, that man is done. I'm finding their messaging on 'face coverings' annoying, they're so desperate not to be seen to do a u-turn they're advising they should be worn whilst at the same time saying we didn't do it earlier because there's no evidence.

People aren't going to wear them when they hear such messages. Be a grown up and explain why they're now needed and why the message has changed.
Agreed. Mind you, I’ve not been able to buy any proper ones anywhere. I’ve seen some local ladies that have taken to sewing their own and selling them, or dodgy looking eBay sellers.

I wear a buff style bandana scarf in the supermarket, but if they try and make this mandatory - they need to significantly improve supply to the public order and above key workers.
 

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1 is baseless speculation that boils down to 'you never know!'. We of course wait to see what happens with 2.
I don't think it's baseless, there is very likely a high number of people who have had the virus before testing came into play and they just won't know until bulk antibody tests are taken. I know of 6 people alone who were tested because they work in NHS, and they barely had any symptoms - all were positive for covid.

I'm sure a lot of people have had the virus, it's just a matter of whether it's enough for a second wave to be prevented.
 

Smores

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I don't think it's baseless, there is very likely a high number of people who have had the virus before testing came into play and they just won't know until bulk antibody tests are taken. I know of 6 people alone who were tested because they work in NHS, and they barely had any symptoms - all were positive for covid.

I'm sure a lot of people have had the virus, it's just a matter of whether it's enough for a second wave to be prevented.
Opinion and anecdotes don't cut it as a basis for scientific opinion. Not when we've had official view from the CSO saying 4% infected so far.
 

JPRouve

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I don't think it's baseless, there is very likely a high number of people who have had the virus before testing came into play and they just won't know until bulk antibody tests are taken. I know of 6 people alone who were tested because they work in NHS, and they barely had any symptoms - all were positive for covid.

I'm sure a lot of people have had the virus, it's just a matter of whether it's enough for a second wave to be prevented.
Two things, the people you are talking about are the most likely to be in contact with the virus(or any virus during an epidemic) and only around 10% of the people tested are positive(in pretty much all countries). It's actually unlikely that a high number of people have had the virus before.
 

VP89

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Two things, the people you are talking about are the most likely to be in contact with the virus(or any virus during an epidemic) and only around 10% of the people tested are positive(in pretty much all countries). It's actually unlikely that a high number of people have had the virus before.
It was just an example, I'm saying that pre-lockdown there would have been many many people who suffered some symptoms, weren't tested and may well have had the virus. I don't find that unlikely.
 

Sparky Rhiwabon

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So people travelling from Ireland to the UK/France won't have to quarantine but those going from the UK/France to Ireland will? Bit messy. Especially given it doesn't appear to apply to people travelling across the border. So people travelling from the UK/France to Ireland could presumably still just come in through NI and skip having to quarantine.
NI is part of the UK
 

VP89

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Opinion and anecdotes don't cut it as a basis for scientific opinion. Not when we've had official view from the CSO saying 4% infected so far.
I understand, but I just ask how is that calculated, exactly?

Pre-lockdown there was a lot of contact amongst everyone with many people experiencing some degree of symptoms. It's impossible to get an accurate figure of how many have been infected so far.
 

JPRouve

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It was just an example, I'm saying that pre-lockdown there would have been many many people who suffered some symptoms, weren't tested and may well have had the virus.
The prevalence of the virus was either lower or equivalent otherwise ICUs would have been swamped way before lockdowns, so it's highly unlikely that a lot of people got the virus before when we know that we were swamped when only around 10% of people that had symptoms and were tested ended up being positive. It would actually be fair to say that not a lot of people got the virus.

The alternative would be that for some reason severe cases all happened at the same time, which is unlikely.
 

Sparky Rhiwabon

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Hancock needs a holiday, that man is done. I'm finding their messaging on 'face coverings' annoying, they're so desperate not to be seen to do a u-turn they're advising they should be worn whilst at the same time saying we didn't do it earlier because there's no evidence.

People aren't going to wear them when they hear such messages. Be a grown up and explain why they're now needed and why the message has changed.
There’s no evidence that they’re of any benefit, Whitty has been saying this for weeks! The only reason they’re talking about them now is to make people feel better or less scared if they have to go on the train etc to work. Placebo effect.
 

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The prevalence of the virus was either lower or equivalent otherwise ICUs would have been swamped way before lockdowns, so it's highly unlikely that a lot of people got the virus before when we know that we were swamped when only around 10% of people that had symptoms and were tested ended up being positive. It would actually be fair to say that not a lot of people got the virus.

The alternative would be that for some reason severe cases all happened at the same time, which is unlikely.
Yeah that is what is baffling about claims that 'most people have already had it and had gone symptomless'. We know what happened in Italy, Spain, New York or UK when cases started piling up, hospitals got full quickly and the curve for positive tests started climbing up. Barring some incredible coincidence, which would have happened in all countries simultaneously, there's just no chance that a lot of people had got it before late Feb/early Mar outbreak.