Mickeza
still gets no respect
France have recommended AZ be used on 55+ only. We’ve gone full circle
France have recommended AZ be used on 55+ only. We’ve gone full circle
Forbidden in France for people over 65 several weeks ago... and now only reserved for 55+...France have recommended AZ be used on 55+ only. We’ve gone full circle
To be fair, the logic has always been sound. No phase 3 evidence of efficacy when first available but we now have some reasonable observational data (especially in Scotland) which supports use in that cohort.France have recommended AZ be used on 55+ only. We’ve gone full circle
Some going.UK vaccinated approx. 1% of the population yesterday (660k doses). 2nd doses just passed 2 million. In related news, hospital deaths are now at less than a tenth of their January peak and continue to fall rapidly.
Loadsa people. Millions of Americans, and most of Israel for a startGetting the Pfizer one on Monday, anyone else got it?
I can see why they’re doing it - it’s just slightly amusing considering where we were 2 weeks ago! They’re not recommending it for now pending further investigation which I think is fair. They have 3 other vaccines available for that age group and plenty of people that need vaccinating over 55 anyway. I didn’t agree with not recommending for 65+ from the start though. Whilst I know the AZ trials didn’t contain enough data to be certain I felt all evidence suggested it would work in over 65s - very much sided with MHRA on that as I did on the prioritisation of first doses whilst supply was so tight and cases were sky rocketing. I have little doubt that saved many lives which is ultimately the goal.To be fair, the logic has always been sound. No phase 3 evidence of efficacy when first available but we now have some reasonable observational data (especially in Scotland) which supports use in that cohort.
Using it only in 55+ seems very cautious but almost completely removes any concerns re this recent issue around DIC (so should help with hesitancy, which has always been a huge issue in France)
Everyone needs to remember that each country makes the decisions that will be of most benefit to its citizens. They’ve had bad experience with vaccines in France in the past, so will be desperate to avoid a repeat performance.
Don't know why he's asking here when he can just go to IsraelLoadsa people. Millions of Americans, and most of Israel for a start
That’s a tantalising headline with very little detail, the feckers!I can see why they’re doing it - it’s just slightly amusing considering where we were 2 weeks ago! They’re not recommending it for now pending further investigation which I think is fair. They have 3 other vaccines available for that age group and plenty of people that need vaccinating over 55 anyway. I didn’t agree with not recommending for 65+ from the start though. Whilst I know the AZ trials didn’t contain enough data to be certain I felt all evidence suggested it would work in over 65s - very much sided with MHRA on that as I did on the prioritisation of first doses whilst supply was so tight and cases were sky rocketing. I have little doubt that saved many lives which is ultimately the goal.
Germany seem to have pinpointed the cause of the clotting and provided people seek medical intervention early enough think it is preventable: https://m.dw.com/en/astrazeneca-german-researchers-discover-thrombosis-trigger/a-56925550
Pre-print in the lancet in the next few days apparently - if you fancy a read in German more on their findings here:That’s a tantalising headline with very little detail, the feckers!
Thanks Why didn't I think of going to Israel to ask around.Loadsa people. Millions of Americans, and most of Israel for a start
my mother got that (1 big bruise) after her 1st dose AZ, doctor thinks it's not a clot, i'm worried.EMA recommendations re seeking medical help after vaccination:
However, if you get any of the following after receiving the COVID-19 Vaccine AstraZeneca:
please seek prompt medical assistance and mention your recent vaccination.
- breathlessness,
- pain in the chest or stomach,
- swelling or coldness in an arm or leg,
- severe or worsening headache or blurred vision after vaccination,
- persistent bleeding,
- multiple small bruises, reddish or purplish spots, or blood blisters under the skin
That's an interesting article, even in its Google translate wobbly form. The comparison with HIT and the consequent treatment approach sounded as if it could be really useful. Let's hope so.Pre-print in the lancet in the next few days apparently - if you fancy a read in German more on their findings here:
https://gth-online.org/wp-content/uploads/2021/03/GTH_Stellungnahme_AstraZeneca_3_19032021.pdf
At the injection site? Possible they just nicked a blood vessel. If she has unexplained bruises elsewhere definitely get checked out.my mother got that (1 big bruise) after her 1st dose AZ, doctor thinks it's not a clot, i'm worried.
Fantastic rates of decline.UK vaccinated approx. 1% of the population yesterday (660k doses). 2nd doses just passed 2 million. In related news, hospital deaths are now at less than a tenth of their January peak and continue to fall rapidly.
https://coronavirus.data.gov.uk/details/healthcarewhat are the figures and the general trend on UK hospitalizations for Covid?
Amazing. Well done to the UK, vaccinated their way out of it, great communication campaign - very high uptake across vulnerable groups. Think many Europe countries will struggle to vaccinate Elderly due to high skepticism.
Nobody is sceptical about the Pfizer, Moderna or Johnson&Johnson vaccine and I think EU has ordered a lot more of those than they have AZ. Sceptisicm is not the problem. Getting enough vaccine is though. In Norway things are going slow. Almost 10% of population have had the first shot, approx. 5% have had both doses. Maybe we could have had a couple of more percent vaccinated if the AZ did not have those huge side effect for some few but we only goy 90k doses in february. I am happy that my nation takes things seriously when it comes to the safety though, because many young people had their lives messed up after the swine flu shot. But the J&J will go faster though, as it is only 1 dose per person. Things will look better in some few months, as long as we can kill this third wave of mutant virus.Amazing. Well done to the UK, vaccinated their way out of it, great communication campaign - very high uptake across vulnerable groups. Think many Europe countries will struggle to vaccinate Elderly due to high skepticism.
Still a long way to go for the UK. We're still on a stay at home message for another 10 days, non-essential retail opens on the 12th of April. I think by May if we're in a positive position on hospital admissions after everything has been opened up again then it'd be fair to say we can see start to see a light at the end of the tunnel. It's a big house of cards though.Amazing. Well done to the UK, vaccinated their way out of it, great communication campaign - very high uptake across vulnerable groups. Think many Europe countries will struggle to vaccinate Elderly due to high skepticism.
Exactly the feeling for me, had mine on Wednesday, aches and constantly needing to sleep insane amounts. But it definitely feels like you’ve been on the piss waking up.Hangover style feelings? I had mine last Friday and Saturday felt like I was on the sauce all day Friday. Weirdly a chicken kebab brought me round on Saturday evening, my arm stopped aching on Wednesday.
Loads of people are sceptical about all of the covid vaccines. It varies between countries and population groups, but fortunately the rate of hesitancy is going down as the vaccine rollout continues. The AZ issues need to be handled well - I'm hoping that the national regulators understand their population well enough to know what "well" means for their country.Nobody is sceptical about the Pfizer, Moderna or Johnson&Johnson vaccine and I think EU has ordered a lot more of those than they have AZ. Sceptisicm is not the problem. Getting enough vaccine is though. In Norway things are going slow. Almost 10% of population have had the first shot, approx. 5% have had both doses. Maybe we could have had a couple of more percent vaccinated if the AZ did not have those huge side effect for some few but we only goy 90k doses in february. I am happy that my nation takes things seriously when it comes to the safety though, because many young people had their lives messed up after the swine flu shot. But the J&J will go faster though, as it is only 1 dose per person. Things will look better in some few months, as long as we can kill this third wave of mutant virus.
Yes I have. Had a sore arm for a day both times and otherwise felt totally well.Thanks Why didn't I think of going to Israel to ask around.
I meant anyone on here with personal experience to share?
I can let you know tomorrow, if I survive it. I just got the call for round 1 of the Pfizer jab, tomorrow at noon.Getting the Pfizer one on Monday, anyone else got it?
My mother got it and has had second dose. No complaints other than slightly sore arm but no worse than any other jab.Getting the Pfizer one on Monday, anyone else got it?
Is that implying the UK doesn't?Nobody is sceptical about the Pfizer, Moderna or Johnson&Johnson vaccine and I think EU has ordered a lot more of those than they have AZ. Sceptisicm is not the problem. Getting enough vaccine is though. In Norway things are going slow. Almost 10% of population have had the first shot, approx. 5% have had both doses. Maybe we could have had a couple of more percent vaccinated if the AZ did not have those huge side effect for some few but we only goy 90k doses in february. I am happy that my nation takes things seriously when it comes to the safety though, because many young people had their lives messed up after the swine flu shot. But the J&J will go faster though, as it is only 1 dose per person. Things will look better in some few months, as long as we can kill this third wave of mutant virus.
Thanks, that's what I heard from most people who have taken it too.Yes I have. Had a sore arm for a day both times and otherwise felt totally well.
Difficult to extrapolate though. I have colleagues who had the pfizer who've had a terrible couple of days after and couldn't even come into work cos they had fevers and chills. Similar with AZ. And some who had AZ who felt pretty fine after.
So wouldn't be able to say really how you'd personally react to it. But exciting nonetheless!
I'm getting it Monday morning UK time.I can let you know tomorrow, if I survive it. I just got the call for round 1 of the Pfizer jab, tomorrow at noon.
Good to hear.My mother got it and has had second dose. No complaints other than slightly sore arm but no worse than any other jab.
English version of that paper:Pre-print in the lancet in the next few days apparently - if you fancy a read in German more on their findings here:
https://gth-online.org/wp-content/uploads/2021/03/GTH_Stellungnahme_AstraZeneca_3_19032021.pdf
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Why isn’t he pointing out that the base rate of 2-5 per million is also a huge underestimation according to these figures? Should be 13 per million.And also a cautionary tale on taking headline stats too literally. The base rate is higher than The minister suggested and depending on the group, the CVT rate varies a lot, with women 20-50 who are pregnant or on the pill at highest risk.
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I think some of them are just sounding offended by the idea that the UK regulators (or they themselves) have ignored adverse reactions and other safety issues. Plus like a lot of doctors they start to panic and get arrogant and defensive when questionedI’m actually getting depressed at the way so many senior UK physicians seem more determined to score points against EU politicians/regulators than to educate. From hanging out on UK doctors message boards I do know that a lot of them were very Brexit-y to begin with (especially the older ones) but this vaccine saga seems to be pushing them over the edge.
Touché!I think some of them are just sounding offended by the idea that the UK regulators (or they themselves) have ignored adverse reactions and other safety issues. Plus like a lot of doctors they start to panic and get arrogant and defensive when questioned
I'm still bothered by the question of "where are the UK cases," and I'm hoping one of them is going to come up with an explanation. If it's the raw numbers - comparing rare incidents to a 10m overall cohort, rather than the maybe 1m who got it in that female 20-50 category - then that needs fixing in how the adverse reactions get monitored.
If it's something else - like the original questions about batch and handling, or any possible differences in what happens in test/treatment terms if someone does go to hospital - then it's potentially important.
I’ve had to stop watching the John Campbell podcast because he’s gone from being subtlety anti-EU to overtly anti-EU - totally offended by the notion Norway may have found something we didn’t know about. Plus he had David Davis of Brexit fame on a few weeks ago - that’s when my spidey sense properly started tinglingWhy isn’t he pointing out that the base rate of 2-5 per million is also a huge underestimation according to these figures? Should be 13 per million.
That still makes the incidence twice as high in women aged 30-50 but nowhere near the ten times as high you’d assume by reading his tweet and not the detail of the table.
I’m actually getting depressed at the way so many senior UK physicians seem more determined to score points against EU politicians/regulators than to educate. From hanging out on UK doctors message boards I do know that a lot of them were very Brexit-y to begin with (especially the older ones) but this vaccine saga seems to be pushing them over the edge.
I saw reference to some similar cases being investigated in the US. Nothing from EU/UK though. It’s all massively complicated by the different ways in which the vaccines are being rolled out.I’ve had to stop watching the John Campbell podcast because he’s gone from being subtlety anti-EU to overtly anti-EU - totally offended by the notion Norway may have found something we didn’t know about. Plus he had David Davis of Brexit fame on a few weeks ago - that’s when my spidey sense properly started tingling
I still haven’t seen any stats on incidents like this after Pfizer/Moderna though. That would be interesting I think.
https://ekstrabladet.dk/nyheder/sam...sfald-mistanke-om-vaccinebivirkninger/8509405Denmark reports another death after vaccination
Two employees from the capital region have been admitted to hospital with serious symptoms within 14 days after vaccination with the Astra Zeneca vaccine, reports Ekstra Bladet in Denmark.
The employees were admitted with symptoms of blood clots in the brain and cerebral haemorrhage, respectively. One of them has now died, the region confirms in an email to the newspaper. Both cases have been reported to the Danish Medicines Agency for further investigation.
Ekstra Bladet writes that this death is the second reported case in Denmark where suspected side effects of vaccination have led to deaths. The first case caused Denmark to pause the use of the Astra Zeneca on 11 March.
Is that implying the UK doesn't?
Not sure why you can't just give credit where it's due.