Lucas will miss the Spurs game and could be facing a lengthy absence according to Paul Joyce at the Express. That's a bit shit.
For the Spurs match I'd probably line up: Mignolet; Johnson, Skrtel, Sakho; Ibe, Can, Henderson, Moreno; Sterling, Sturridge, Coutinho.
I think Pochettino will start the same players that started against Arsenal:
Lloris, Walker Dier, Vertonghen, Rose, Bentaleb, Mason, Dembele, Lamela, Eriksen, Kane ... although possibly he'll rest Rose and play the more defensive-minded Davies at LB. If he does start Davies, then Spurs will break the record we set against Arsenal of fielding the youngest starting XI in the Prem this season.
Dier and not Fazio because he'll want pace at the back to better handle your quick strikers/attackers, not least in relation to balls over the top of our usually high defensive line. And also because Fazio's arial strength won't be especially needed against your strikers/playing style.
Perhaps I'm over-confident from Spurs having recently despatched both Arsenal and Chelsea in convincing style, but I think we have a decent chance of winning this.